Compile Data Set for Download or QSAR
Report error Found 327 Enz. Inhib. hit(s) with Target = 'Caspase-6'
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50117678(CHEMBL3613794)
Affinity DataKd:  470nMAssay Description:Inhibition of Pro-caspase-6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50117679(CHEMBL3613793)
Affinity DataKd:  2.90E+3nMAssay Description:Inhibition of Pro-caspase-6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM10323(JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50273339((S)-1-(4-Fluorobenzyl)-5-(2-((1-(2-fluoroethyl)-1H...)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50273991((S)-1-(4-Fluorobenzyl)-5-(2-(pyrimidin-4-yloxymeth...)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50273990((S)-1-(4-Fluorobenzyl)-5-(2-(tetrahydro-2H-pyran-4...)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50273989((S)-1-(4-Fluorobenzyl)-5-(2-(3,5-difluorophenoxyme...)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50273929((S)-1-(4-Fluorobenzyl)-5-(2-(2,4-difluorophenoxyme...)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50273928((S)-1-(4-Fluorobenzyl)-5-(2-(3-fluorophenoxymethyl...)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50273927((S)-1-(4-Fluorobenzyl)-5-(2-(4-fluorophenoxymethyl...)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50273926(1-(4-Fluorobenzyl)-5-(pyrrolidine-1-sulfonyl)isati...)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM10331((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50200305((S)-1-(4-iodobenzyl)-5-(2-phenoxymethyl-pyrrolidin...)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50273338((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50273337((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50273992((S)-1-(2-Propynyl)-5-(2-(2,4-difluorophenoxymethyl...)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50117678(CHEMBL3613794)
Affinity DataKd:  270nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623926(CHEMBL5395946)
Affinity DataKd:  470nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623927(CHEMBL5419392)
Affinity DataKd:  850nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623928(CHEMBL5440664)
Affinity DataKd:  180nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623929(CHEMBL5415724)
Affinity DataKd:  9.53E+4nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623930(CHEMBL5417769)
Affinity DataKd:  620nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623931(CHEMBL5427104)
Affinity DataKd:  1.15E+3nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623932(CHEMBL5426757)
Affinity DataKd:  4.01E+3nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623933(CHEMBL5429254)
Affinity DataKd:  1.28E+4nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623934(CHEMBL5433593)
Affinity DataKd:  1.19E+3nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623935(CHEMBL5423957)
Affinity DataKd:  9.80E+5nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623936(CHEMBL5424099)
Affinity DataKd:  1.82E+5nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623937(CHEMBL5413901)
Affinity DataKd:  1.06E+5nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623938(CHEMBL5394982)
Affinity DataKd:  5.08E+3nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623939(CHEMBL5429758)
Affinity DataKd:  9.79E+3nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623940(CHEMBL5424498)
Affinity DataKd:  5.51E+4nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623941(CHEMBL5429477)
Affinity DataKd:  1.33E+4nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623942(CHEMBL5431147)
Affinity DataKd:  760nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623943(CHEMBL5400834)
Affinity DataKd:  2.12E+4nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623944(CHEMBL5399818)
Affinity DataKd:  220nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623944(CHEMBL5399818)
Affinity DataKd:  220nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623944(CHEMBL5399818)
Affinity DataKd:  220nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623945(CHEMBL5399563)
Affinity DataKd:  1.16E+3nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623946(CHEMBL5419029)
Affinity DataKd:  1.36E+3nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623946(CHEMBL5419029)
Affinity DataKd:  1.36E+3nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623947(CHEMBL5399398)
Affinity DataKd:  2.13E+3nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623947(CHEMBL5399398)
Affinity DataKd:  2.13E+3nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623948(CHEMBL5422136)
Affinity DataKd:  310nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623949(CHEMBL5419962)
Affinity DataKd:  80nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623950(CHEMBL5415444)
Affinity DataKd:  1.10E+6nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623951(CHEMBL5409183)
Affinity DataKd:  4.61E+4nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623952(CHEMBL5423749)
Affinity DataKd:  970nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623953(CHEMBL5395330)
Affinity DataKd:  9.24E+3nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCaspase-6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50623954(CHEMBL5415854)
Affinity DataKd:  4.79E+3nMAssay Description:Binding affinity at Caspase 6 (1 to 293) C163A mutant (unknown origin) expressed in Escherichia coli BL21-Gold (DE3) by SPR response measuredMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
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