Compile Data Set for Download or QSAR
Report error Found 77 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 26B1'
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50253810(R115866 | CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4...)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50253810(R115866 | CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4...)
Affinity DataIC50: 0.460nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM393281(US9963439, R116010)
Affinity DataIC50: 3.10nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157605(Liazal | R-75251 | Liarozole | US9963439, Liarozol...)
Affinity DataIC50: 18nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157605(Liazal | R-75251 | Liarozole | US9963439, Liarozol...)
Affinity DataIC50: 18nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 140nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM557292(US11358933, Compound 026)
Affinity DataIC50: 200nMAssay Description:CYP26 inhibitory activities of various compounds.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476235(US10874634, Cmpd No. 17 | US11364220, Compound 17)
Affinity DataIC50: 290nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476235(US10874634, Cmpd No. 17 | US11364220, Compound 17)
Affinity DataIC50: 290nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM557299(US11358933, Compound 034)
Affinity DataIC50: 500nMAssay Description:CYP26 inhibitory activities of various compounds.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM31886(CHEMBL309282 | CD564)
Affinity DataIC50: 520nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476228(US10874634, Cmpd No. 10 | US11364220, Compound 10)
Affinity DataIC50: 550nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476228(US10874634, Cmpd No. 10 | US11364220, Compound 10)
Affinity DataIC50: 550nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157722(CHEMBL3787323)
Affinity DataIC50: 680nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157724(CHEMBL3787564 | US9963439, Compound B)
Affinity DataIC50: 930nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157727(CHEMBL3786184)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157721(CHEMBL3786620)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50033067(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157729(CHEMBL3787691)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157731(CHEMBL3785511 | US9963439, Compound C)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157604(CHEMBL3786324)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476180(US10874634, Cmpd No. 02 | US11364220, Compound 02)
Affinity DataIC50: 2.06E+3nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476180(US10874634, Cmpd No. 02 | US11364220, Compound 02)
Affinity DataIC50: 2.06E+3nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM557298(US11358933, Compound 032)
Affinity DataIC50: 2.30E+3nMAssay Description:CYP26 inhibitory activities of various compounds.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157718(CHEMBL3785701)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157730(CHEMBL3785557)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157723(CHEMBL3786927)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157608(CHEMBL95949)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157726(CHEMBL3786043)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157719(CHEMBL3785624)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157728(CHEMBL3785761)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157720(CHEMBL3786340)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM557293(US11358933, Compound 027)
Affinity DataIC50: 8.80E+3nMAssay Description:CYP26 inhibitory activities of various compounds.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476173(US10874634, Cmpd No. 01 | US11364220, Compound 01)
Affinity DataIC50: 8.81E+3nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476173(US10874634, Cmpd No. 01 | US11364220, Compound 01)
Affinity DataIC50: 8.81E+3nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476236(US10874634, Cmpd No. 18 | US11364220, Compound 18)
Affinity DataIC50: 9.07E+3nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476236(US10874634, Cmpd No. 18 | US11364220, Compound 18)
Affinity DataIC50: 9.07E+3nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157717(CHEMBL3786581)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476222(US10874634, Cmpd No. 05 | US11364220, Compound 05)
Affinity DataIC50: 1.15E+4nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476222(US10874634, Cmpd No. 05 | US11364220, Compound 05)
Affinity DataIC50: 1.15E+4nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476234(US10874634, Cmpd No. 16 | US11364220, Compound 16)
Affinity DataIC50: 1.19E+4nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476234(US10874634, Cmpd No. 16 | US11364220, Compound 16)
Affinity DataIC50: 1.19E+4nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50033077(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476226(US10874634, Cmpd No. 09 | US11364220, Compound 09)
Affinity DataIC50: 1.42E+4nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476226(US10874634, Cmpd No. 09 | US11364220, Compound 09)
Affinity DataIC50: 1.42E+4nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157611(CHEMBL3787627)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM557291(US11358933, Compound 025)
Affinity DataIC50: 1.79E+4nMAssay Description:CYP26 inhibitory activities of various compounds.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM557297(US11358933, Compound 031)
Affinity DataIC50: 1.83E+4nMAssay Description:CYP26 inhibitory activities of various compounds.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM476217(US10874634, Cmpd No. 04 | US11364220, Compound 04)
Affinity DataIC50: 1.89E+4nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
US Patent

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