Compile Data Set for Download or QSAR
Report error Found 548 Enz. Inhib. hit(s) with Target = 'Cytosolic phospholipase A2'
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50205515(4-{2-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl...)
Affinity DataKd:  139nMAssay Description:Binding affinity to human cPLA2 alpha by isothermal calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50226792(4-(3-(1-benzhydryl-5-chloro-2-(2-((3,4-dichlorophe...)
Affinity DataIC50: 0.540nMAssay Description:Inhibition of cPLA2alpha isolated from human U937 cell cytoplasm assessed as suppression of [14C]arachidonic acid release from L-alpha-1-palmitoyl-2-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185354(3-methylhydrogen 1-[3-(4-decyloxyphenoxy)-2-oxopro...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185348(3-methylhydrogen 1-[3-(4-octylphenoxy)-2-oxopropyl...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50085993((E)-N-(((2S,4R)-4-((biphenyl-2-ylmethyl)(isobutyl)...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50085984(N-[1-[2-(2,4-Difluoro-benzoyl)-benzoyl]-4-(3-isobu...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50085986(N-{4-(Biphenyl-2-ylmethyl-isobutyl-amino)-1-[2-(4-...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2 beta(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50110881(4-{2-Oxo-3-[4-(5-phenyl-pentylsulfanyl)-phenoxy]-p...)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by bilayer assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2 gamma(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50097334(N-[(2S,4R)-1-[2-(2,4-Difluoro-benzoyl)-benzoyl]-4-...)
Affinity DataIC50: 4.20nMAssay Description:Concentration required to inhibit human Cytosolic phospholipase A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185354(3-methylhydrogen 1-[3-(4-decyloxyphenoxy)-2-oxopro...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human isolated cPLA2-alpha by vesicle assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185348(3-methylhydrogen 1-[3-(4-octylphenoxy)-2-oxopropyl...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human isolated cPLA2-alpha by vesicle assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185348(3-methylhydrogen 1-[3-(4-octylphenoxy)-2-oxopropyl...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human platelet cPLA2-alpha assessed as arachidonic acid release by vesicle assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185348(3-methylhydrogen 1-[3-(4-octylphenoxy)-2-oxopropyl...)
Affinity DataIC50: 5nMAssay Description:Inhibition of cPLA2 from human platelets by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277800(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indazole-5-c...)
Affinity DataIC50: 5nMAssay Description:Inhibition of cPLA2 from human platelets by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277800(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indazole-5-c...)
Affinity DataIC50: 5nMAssay Description:Inhibition of cPLA2 in human platelets assessed as arachidonic acid releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50085987(4-(2,4-Dioxo-thiazolidin-5-ylidenemethyl)-N-[1-[2-...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50292791(4-{3-[2-{2-[({2-[(4-Acetylpiperazin-1-yl)methyl]be...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human cytosolic PLA2alpha by GLU micelle assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50085994(N-{4-(Biphenyl-2-ylmethyl-isobutyl-amino)-1-[2-(2,...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185351(3-acetyl-1-[3-(4-octylphenoxy)-2-oxopropyl]indole-...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50056707(CHEMBL3326971)
Affinity DataIC50: 7nMAssay Description:Inhibition of cPLA2alpha isolated from human U937 cell cytoplasm assessed as suppression of [14C]arachidonic acid release from L-alpha-1-palmitoyl-2-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50056741(CHEMBL3327088)
Affinity DataIC50: 7nMAssay Description:Inhibition of cPLA2alpha isolated from human U937 cell cytoplasm assessed as suppression of [14C]arachidonic acid release from L-alpha-1-palmitoyl-2-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110846(4-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxy]-benzoic a...)
Affinity DataIC50: 7nMAssay Description:Inhibition of cPLA2 alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185350(1-[3-(4-decyloxyphenoxy)-2-oxopropyl]indole-5-carb...)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2 beta(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50110846(4-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxy]-benzoic a...)
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by bilayer assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185349(3-formyl-1-[3-(4-octylphenoxy)-2-oxopropyl]indole-...)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50226793(4-{3-[5-Chloro-2-(2-{[(2,6-dimethylbenzyl)sulfonyl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human cytosolic PLA2alpha by GLU micelle assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50292792(4-(3-{5-Chloro-1-(diphenylmethyl)-2-[2-({[2-(morph...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human cytosolic PLA2alpha by GLU micelle assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50233832(CHEMBL1800991)
Affinity DataIC50: 10nMAssay Description:Inhibition of human platelet cytosolic phospholipase alpha-2 using 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycerol as ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50233835(CHEMBL4097068)
Affinity DataIC50: 10nMAssay Description:Inhibition of human platelet cytosolic phospholipase alpha-2 using 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycerol as ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185345(3-cyano-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indo...)
Affinity DataIC50: 11nMAssay Description:Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110846(4-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxy]-benzoic a...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human isolated cPLA2-alpha by vesicle assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110846(4-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxy]-benzoic a...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human platelet cPLA2-alpha assessed as arachidonic acid release by vesicle assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50056712(CHEMBL3326966)
Affinity DataIC50: 11nMAssay Description:Inhibition of cPLA2alpha isolated from human U937 cell cytoplasm assessed as suppression of [14C]arachidonic acid release from L-alpha-1-palmitoyl-2-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110846(4-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxy]-benzoic a...)
Affinity DataIC50: 11nMAssay Description:Inhibition of cPLA2 from human platelets by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110846(4-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxy]-benzoic a...)
Affinity DataIC50: 11nMAssay Description:Inhibition of cPLA2 in human platelets assessed as arachidonic acid releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110846(4-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxy]-benzoic a...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human platelet cytosolic phospholipase alpha-2 using 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycerol as ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185351(3-acetyl-1-[3-(4-octylphenoxy)-2-oxopropyl]indole-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of cPLA2 from human platelets by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50233833(CHEMBL1085637)
Affinity DataIC50: 12nMAssay Description:Inhibition of human platelet cytosolic phospholipase alpha-2 using 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycerol as ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50292790(4-(3-{5-Chloro-1-(diphenylmethyl)-2-[2-({[2-(piper...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human cytosolic PLA2alpha by GLU micelle assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50056740(CHEMBL3327089)
Affinity DataIC50: 14nMAssay Description:Inhibition of cPLA2alpha isolated from human U937 cell cytoplasm assessed as suppression of [14C]arachidonic acid release from L-alpha-1-palmitoyl-2-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185345(3-cyano-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indo...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human isolated cPLA2-alpha by vesicle assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50056708(CHEMBL3326970)
Affinity DataIC50: 15nMAssay Description:Inhibition of cPLA2alpha isolated from human U937 cell cytoplasm assessed as suppression of [14C]arachidonic acid release from L-alpha-1-palmitoyl-2-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185345(3-cyano-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indo...)
Affinity DataIC50: 15nMAssay Description:Inhibition of cPLA2 from human platelets by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50233834(CHEMBL4079052)
Affinity DataIC50: 15nMAssay Description:Inhibition of human platelet cytosolic phospholipase alpha-2 using 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycerol as ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185349(3-formyl-1-[3-(4-octylphenoxy)-2-oxopropyl]indole-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human isolated cPLA2-alpha by vesicle assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185351(3-acetyl-1-[3-(4-octylphenoxy)-2-oxopropyl]indole-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human isolated cPLA2-alpha by vesicle assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50185349(3-formyl-1-[3-(4-octylphenoxy)-2-oxopropyl]indole-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of cPLA2 from human platelets by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277799(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-benzo[d][1,2...)
Affinity DataIC50: 16nMAssay Description:Inhibition of cPLA2 from human platelets by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50277799(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-benzo[d][1,2...)
Affinity DataIC50: 16nMAssay Description:Inhibition of cPLA2 in human platelets assessed as arachidonic acid releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2 beta(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50110859({4-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxy]-phenyl}-...)
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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