Compile Data Set for Download or QSAR
Report error Found 88 Enz. Inhib. hit(s) with Target = 'DDB1- and CUL4-associated factor 15'
TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627140BDBM50627140(CHEMBL5429394)
Affinity DataKd:  31nMAssay Description:Binding affinity to Avi-tagged DCAF1 (1073 to 1399 residues) (unknown origin) expressed in baculovirus infected in Sf9 insect cells by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627138BDBM50627138(CHEMBL5397181)
Affinity DataKd:  47nMAssay Description:Binding affinity to Avi-tagged DCAF1 (1073 to 1399 residues) (unknown origin) expressed in baculovirus infected in Sf9 insect cells by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627139BDBM50627139(CHEMBL5431028)
Affinity DataKd:  83nMAssay Description:Binding affinity to Avi-tagged DCAF1 (1073 to 1399 residues) (unknown origin) expressed in baculovirus infected in Sf9 insect cells by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627137BDBM50627137(CHEMBL5439774)
Affinity DataKd:  98nMAssay Description:Binding affinity to Avi-tagged DCAF1 (1073 to 1399 residues) (unknown origin) expressed in baculovirus infected in Sf9 insect cells by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627136BDBM50627136(CHEMBL5424590)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to Avi-tagged DCAF1 (1073 to 1399 residues) (unknown origin) expressed in baculovirus infected in Sf9 insect cells by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633527BDBM633527(US11807606, Compound 11)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708590BDBM708590(US20240425486, Compound 10)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633528BDBM633528(US11807606, Compound 12)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708591BDBM708591(US20240425486, Compound 11)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708588BDBM708588(US20240425486, Compound 7)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708589BDBM708589(US20240425486, Compound 8)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633523BDBM633523(US11807606, Compound 7)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633525BDBM633525(US11807606, Compound 9)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633526BDBM633526(US11807606, Compound 10)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708599BDBM708599(US20240425486, Compound 22)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633537BDBM633537(US11807606, Compound 21)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708596BDBM708596(US20240425486, Compound 17)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708597BDBM708597(US20240425486, Compound 18)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708594BDBM708594(US20240425486, Compound 15)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708595BDBM708595(US20240425486, Compound 16)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708592BDBM708592(US20240425486, Compound 12)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708593BDBM708593(US20240425486, Compound 14)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633519BDBM633519(US11807606, Compound 3)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633520BDBM633520(US11807606, Compound 4)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633521BDBM633521(US11807606, Compound 5)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633522BDBM633522(US11807606, Compound 6)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633517BDBM633517(US11807606, Compound 1)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633518BDBM633518(US11807606, Compound 2)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633543BDBM633543(US11807606, Compound 27)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708606BDBM708606(US20240425486, Compound 36)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633544BDBM633544(US11807606, Compound 28)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708607BDBM708607(US20240425486, Compound 37)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708604BDBM708604(US20240425486, Compound 34)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708605BDBM708605(US20240425486, Compound 35)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708603BDBM708603(US20240425486, Compound 31)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708600BDBM708600(US20240425486, Compound 23)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708601BDBM708601(US20240425486, Compound 25)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708614BDBM708614(US20240425486, Compound 49)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708612BDBM708612(US20240425486, Compound 47)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633554BDBM633554(US11807606, Compound 38)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708613BDBM708613(US20240425486, Compound 48)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708610BDBM708610(US20240425486, Compound 42)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708608BDBM708608(US20240425486, Compound 38)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 708609BDBM708609(US20240425486, Compound 41)
Affinity DataIC50: 5.50E+3nMAssay Description:DCAF15 interactions with test compounds were monitored using HTRF competition assays (Cisbio, Bedford, MA). Test compounds were first collected in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627135BDBM50627135(CHEMBL5409735)
Affinity DataKd:  5.60E+3nMAssay Description:Binding affinity to Avi-tagged DCAF1 (1073 to 1399 residues) (unknown origin) expressed in baculovirus infected in Sf9 insect cells by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633529BDBM633529(US11807606, Compound 13)
Affinity DataEC50: >1.00E+4nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633530BDBM633530(US11807606, Compound 14)
Affinity DataEC50: >1.00E+4nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633524BDBM633524(US11807606, Compound 8)
Affinity DataEC50: >1.00E+4nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633535BDBM633535(US11807606, Compound 19)
Affinity DataEC50: >1.00E+4nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633536BDBM633536(US11807606, Compound 20)
Affinity DataEC50: >1.00E+4nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

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