Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with Target = 'DNA-3-methyladenine glycosylase'
TargetDNA-3-methyladenine glycosylase(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2016
Entry Details Article
PubMed
TargetDNA-3-methyladenine glycosylase 1(Escherichia coli (strain K12))TBA
LigandPNGBDBM50488844(3-BENZYLADENINE)
Affinity DataIC50: 400nMAssay Description:Inhibition of Escherichia coli DNA-3-methyladenine glycosylase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetDNA-3-methyladenine glycosylase 1(Escherichia coli (strain K12))TBA
LigandPNGBDBM50488842(3-BUTYLADENINE)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Escherichia coli DNA-3-methyladenine glycosylase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetDNA-3-methyladenine glycosylase(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM67690(SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2016
Entry Details Article
PubMed
TargetDNA-3-methyladenine glycosylase(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2016
Entry Details Article
PubMed
TargetDNA-3-methyladenine glycosylase(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human AAG using HXO2/Loop01 oligonucleotide as substrate incubated for 2 hrs by colorimetric based microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetDNA-3-methyladenine glycosylase(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM23223(Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2016
Entry Details Article
PubMed
TargetDNA-3-methyladenine glycosylase 1(Escherichia coli (strain K12))TBA
LigandPNGBDBM50488843(3-PROPYLADENINE)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Escherichia coli DNA-3-methyladenine glycosylase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetDNA-3-methyladenine glycosylase(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human purified MPG binding to immobilized ethenoadenine containing 5'-TCGAGGATCCTGAGCTCGAGTCGACGXTCGCGAATTCTGCGGATCCAAGC-3' duplex olig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2016
Entry Details Article
PubMed
TargetDNA-3-methyladenine glycosylase 1(Escherichia coli (strain K12))TBA
LigandPNGBDBM50488845(3-ETHYLADENINE)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Escherichia coli DNA-3-methyladenine glycosylase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetDNA-3-methyladenine glycosylase(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MPG in human A549 cell extracts at 50 to 300 uM using 1,N6 ethenoadenine containing 32P-labeled duplex oligonucleotide substrates by ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2016
Entry Details Article
PubMed
TargetDNA-3-methyladenine glycosylase(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50559764(CHEMBL4751946)
Affinity DataIC50: 1.57E+5nMAssay Description:Inhibition of human AAG using HXO2/Loop01 oligonucleotide as substrate incubated for 2 hrs by colorimetric based microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetDNA-3-methyladenine glycosylase(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MPG in human HeLa cell extracts at 50 to 300 uM using 1,N6 ethenoadenine containing 32P-labeled duplex oligonucleotide substrates by ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2016
Entry Details Article
PubMed
TargetDNA-3-methyladenine glycosylase 1(Escherichia coli (strain K12))TBA
LigandPNGBDBM50488841(CHEBI:38635 | 3-METHYLADENINE)
Affinity DataIC50: 1.50E+6nMAssay Description:Inhibition of Escherichia coli DNA-3-methyladenine glycosylase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article