Compile Data Set for Download or QSAR
Report error Found 2047 Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 2'
TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM27950(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM670787(US20240140938, Example 11 | ((R)-3-(5-(difluoromet...)
Affinity DataIC50: 0.330nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM670906(US20240140938, Example 119 | 3-(3-(difluoromethoxy...)
Affinity DataIC50: 0.330nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM530846(WO2022076496, Example 137)
Affinity DataIC50: 0.510nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076496

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM486396(US10947222, Example 27-A)
Affinity DataIC50: 0.520nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM323669((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...)
Affinity DataIC50: 0.600nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM323669((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...)
Affinity DataIC50: 0.600nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM530797(WO2022076496, Example 94)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076496

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM689235(US20240254114, Example 54 | 5-((5-chloro-3-(2,2-di...)
Affinity DataIC50: 0.600nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM670826((6R)-3-(5-(difluoromethoxy)-2- fluorophenyl)-1-(1,...)
Affinity DataIC50: 0.600nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM670776(US20240140938, Example 2 | (R)-3-(3-(difluorometho...)
Affinity DataIC50: 0.630nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM435283(US10568876, Example 46 | ethyl 5-(2-(tert-butylcar...)
Affinity DataIC50: 0.660nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM530621(WO2022076495, EXAMPLE 65 | 1-(5-(difluoromethoxy)-...)
Affinity DataIC50: 0.700nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM530621(WO2022076495, EXAMPLE 65 | 1-(5-(difluoromethoxy)-...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human DGAT2 expressed in sf9 insect cell membrane assessed as reduction in 13C18-triolein product formation using 13C oleoyl-CoA as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM689215(US20240254114, Example 17 | 6-((5-chloro-3-(2,2,2-...)
Affinity DataIC50: 0.700nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM486376(3-(3-cyclopropylphenyl)-1-(5- fluoropyridin-2-yl)-...)
Affinity DataIC50: 0.730nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM486393(3-(5-(difluoromethoxy)pyridin- 3-yl)-1-(4-fluoroph...)
Affinity DataIC50: 0.770nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM486375(3-(3-cyclopropylphenyl)-1-(5- fluoropyridin-2-yl)-...)
Affinity DataIC50: 0.790nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM530766(WO2022076496, Example 63)
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076496

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM689216(US20240254114, Example 18 | 6-((5-chloro-3-(2,2,2-...)
Affinity DataIC50: 0.800nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM689244(US20240254114, Example 63b | 5-[2-(2,2-difluoroeth...)
Affinity DataIC50: 0.800nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM627271(3-[3-(cyclopropoxy)phenyl]- 1-isopropyl-N-(3-methy...)
Affinity DataIC50: 0.900nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM627271(3-[3-(cyclopropoxy)phenyl]- 1-isopropyl-N-(3-methy...)
Affinity DataIC50: 0.900nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM689213(US20240254114, Example 15 | 6-((3-(2,2-difluoroeth...)
Affinity DataIC50: 0.900nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM486386(3-(3-(difluoromethoxy)phenyl)-1-(5- fluoropyrimidi...)
Affinity DataIC50: 0.910nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM486372(3-(3-(difluoromethoxy)phenyl)-1-(5- fluoropyridin-...)
Affinity DataIC50: 0.940nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM486373(3-(3-(difluoromethoxy)phenyl)-1-(5- fluoropyridin-...)
Affinity DataIC50: 1nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM530630(WO2022076495, EXAMPLE 70a)
Affinity DataIC50: 1nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM530728(WO2022076496, Example 26)
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076496

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM627182(3-(3-(difluoromethoxy)phenyl)-4- fluoro-1-isopropy...)
Affinity DataIC50: 1nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM627288(3-(5-(difluoromethoxy)-2- fluorophenyl)-1-isopropy...)
Affinity DataIC50: 1nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM50594461(CHEMBL5202996)
Affinity DataIC50: 1nMAssay Description:Inhibition of human DGAT2 expressed in sf9 insect cell membrane assessed as reduction in 13C18-triolein product formation using 13C oleoyl-CoA as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM627288(3-(5-(difluoromethoxy)-2- fluorophenyl)-1-isopropy...)
Affinity DataIC50: 1nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM486408(3-[3-(difluoromethoxy)phenyl]-N- (1,1-dioxidotetra...)
Affinity DataIC50: 1.10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM530622(WO2022076495, EXAMPLE 66a)
Affinity DataIC50: 1.10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM50594459(CHEMBL5179522)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human DGAT2 expressed in sf9 insect cell membrane assessed as reduction in 13C18-triolein product formation using 13C oleoyl-CoA as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM435291(US10568876, Example 54 | methyl 3-(2-((1-methylcyc...)
Affinity DataIC50: 1.13nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM530847(WO2022076496, Example 138)
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076496

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM689214(US20240254114, Example 16 | 6-((3-(2,2-difluoroeth...)
Affinity DataIC50: 1.20nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM215552(US9296745, 109-A | US9296745, 190 | US9296745, 109...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human DGAT2 assessed as reduction in synthesis of triglycerol in human hepatocyte using [14C]glycerol as substrate preincubated for 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM689212(US20240254114, Example 14 | 6-((5-fluoro-3-(2,2,2-...)
Affinity DataIC50: 1.30nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM323644((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...)
Affinity DataIC50: 1.40nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM323644((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...)
Affinity DataIC50: 1.40nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM517319(US11104690, Example 136-A | 3-[3- (difluoromethoxy...)
Affinity DataIC50: 1.40nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM323668(N-((S)-2,3-dihydro-1H- inden-1-yl)-2-((R)-3-(2- et...)
Affinity DataIC50: 1.5nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM323668(N-((S)-2,3-dihydro-1H- inden-1-yl)-2-((R)-3-(2- et...)
Affinity DataIC50: 1.5nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM530640(WO2022076495, EXAMPLE 75a)
Affinity DataIC50: 1.5nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM627228(3-[3-(difluoromethoxy)phenyl]- N-(3-methyl-1,1-dio...)
Affinity DataIC50: 1.5nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM50594462(CHEMBL5194578)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human DGAT2 expressed in sf9 insect cell membrane assessed as reduction in 13C18-triolein product formation using 13C oleoyl-CoA as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
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