Report error Found 4295 Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17'
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 7.00E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 1.70E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 3.00E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 2.40E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 5.00E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 2.50E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 1.00E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 2.00E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 3.50E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 1.05E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.0260nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0660nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using pro-TNFalpha peptide Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.210nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.220nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.230nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.260nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.280nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.300nMAssay Description:Inhibition of TACE (unknown origin) using fluorogenic LAQAVRSSSR peptide as a substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.310nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.330nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.330nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.398nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.400nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.400nMAssay Description:Inhibition of TACE (unknown origin) using fluorogenic LAQAVRSSSR peptide as a substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.410nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.420nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.430nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.440nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.440nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.480nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.480nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
