Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [1-770,'NPG',771-1210,T790M]'
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Celyn Therapeutics

US Patent
LigandPNGBDBM770154((13Z)-23-[(3-fluoro-2- methoxyphenyl)amino]-8,11-d...)
Affinity DataEC50: <1nMAssay Description:Table B: The enzymatic assay used to determine activity was a Luminescence assay using a Microplate Reader ClarioStar Plus. The enzymatic reaction wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Celyn Therapeutics

US Patent
LigandPNGBDBM770152((13E)-23-[(3-fluoro-2- methoxyphenyl)amino]-8,11-d...)
Affinity DataEC50:  3nMAssay Description:Table B: The enzymatic assay used to determine activity was a Luminescence assay using a Microplate Reader ClarioStar Plus. The enzymatic reaction wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Celyn Therapeutics

US Patent
LigandPNGBDBM770153(23-[(3-fluoro-2-methoxyphenyl)amino]-8,11- dioxa-5...)
Affinity DataEC50:  3nMAssay Description:Table B: The enzymatic assay used to determine activity was a Luminescence assay using a Microplate Reader ClarioStar Plus. The enzymatic reaction wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Celyn Therapeutics

US Patent
LigandPNGBDBM770155((16R)-23-[(3-fluoro-2- methoxyphenyl)amino]-8,11-d...)
Affinity DataEC50:  3nMAssay Description:Table B: The enzymatic assay used to determine activity was a Luminescence assay using a Microplate Reader ClarioStar Plus. The enzymatic reaction wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Celyn Therapeutics

US Patent
LigandPNGBDBM770156((16S)-23-[(3-fluoro-2- methoxyphenyl)amino]-8,11-d...)
Affinity DataEC50:  3nMAssay Description:Table B: The enzymatic assay used to determine activity was a Luminescence assay using a Microplate Reader ClarioStar Plus. The enzymatic reaction wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Celyn Therapeutics

US Patent
LigandPNGBDBM731071(US20250122202, Example 26)
Affinity DataIC50: 6.31nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Celyn Therapeutics

US Patent
LigandPNGBDBM731070(US20250122202, Example 109)
Affinity DataIC50: 7.27nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Celyn Therapeutics

US Patent
LigandPNGBDBM731065(US20250122202, Example 115)
Affinity DataIC50: 8.16nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Celyn Therapeutics

US Patent
LigandPNGBDBM730779(US20250122202, Example 60)
Affinity DataIC50: 8.80nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Celyn Therapeutics

US Patent
LigandPNGBDBM731066(US20250122202, Example 71)
Affinity DataIC50: 9.27nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Celyn Therapeutics

US Patent
LigandPNGBDBM731067(US20250122202, Example 104)
Affinity DataIC50: 11.4nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Celyn Therapeutics

US Patent
LigandPNGBDBM731064(US20250122202, Example 114)
Affinity DataIC50: 18.2nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Celyn Therapeutics

US Patent
LigandPNGBDBM731069(US20250122202, Example 64)
Affinity DataIC50: 93.6nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent