Compile Data Set for Download or QSAR
Report error Found 106 Enz. Inhib. hit(s) with Target = 'Fascin'
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526223(CHEMBL4455723)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526224(CHEMBL4451624)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526228(CHEMBL4564438)
Affinity DataKd:  2.70E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526229(CHEMBL4544795)
Affinity DataKd:  2.70E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526230(CHEMBL4457641)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526231(CHEMBL4527032)
Affinity DataKd:  6.60E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526232(CHEMBL4439645)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526233(CHEMBL4574047)
Affinity DataKd:  2.10E+4nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526234(CHEMBL4448440)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526239(CHEMBL4592515)
Affinity DataKd:  9.20E+4nMAssay Description:Binding affinity to fascin 1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526225(CHEMBL4452711)
Affinity DataKd:  50nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by ITCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526237(CHEMBL4543704)
Affinity DataKd:  7.60E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526241(CHEMBL4461540)
Affinity DataKd:  270nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526240(CHEMBL4566108)
Affinity DataKd:  600nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526227(CHEMBL4574198)
Affinity DataKd:  250nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526226(CHEMBL4559691)
Affinity DataKd:  580nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526242(CHEMBL4472315)
Affinity DataKd:  1.03E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526243(CHEMBL4576435)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526244(CHEMBL4537924)
Affinity DataKd: >5.00E+5nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526245(CHEMBL4470509)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526238(CHEMBL4469510)
Affinity DataKd:  2.93E+4nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526236(CHEMBL4584583)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350100(US10208043, # 1 | 5-(3,4-dichlorobenzyl)-1- (S,S,-...)
Affinity DataKd:  2.93E+4nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526246(CHEMBL4539975)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526247(CHEMBL4574928)
Affinity DataKd:  2.92E+4nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526248(CHEMBL4462533)
Affinity DataKd:  4.60E+4nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526225(CHEMBL4452711)
Affinity DataKd:  90nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526235(CHEMBL4516481)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526225(CHEMBL4452711)
Affinity DataIC50: 240nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526241(CHEMBL4461540)
Affinity DataIC50: 330nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50: 500nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50: 500nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50: 500nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50: 500nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526227(CHEMBL4574198)
Affinity DataIC50: 510nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350111(US10208043, # 12 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 539nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350111(US10208043, # 12 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 539nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526226(CHEMBL4559691)
Affinity DataIC50: 630nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526240(CHEMBL4566108)
Affinity DataIC50: 630nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350102(US10208043, # 3 | 2-chloro-N-(6- chlorobenzo[d]thi...)
Affinity DataIC50: 652nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350102(US10208043, # 3 | 2-chloro-N-(6- chlorobenzo[d]thi...)
Affinity DataIC50: 652nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350107(US10208043, # 8 | N-(3-(1H-1,2,4-triazol-3- ylthio...)
Affinity DataIC50: 683nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350107(US10208043, # 8 | N-(3-(1H-1,2,4-triazol-3- ylthio...)
Affinity DataIC50: 683nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350100(US10208043, # 1 | 5-(3,4-dichlorobenzyl)-1- (S,S,-...)
Affinity DataIC50: 734nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350100(US10208043, # 1 | 5-(3,4-dichlorobenzyl)-1- (S,S,-...)
Affinity DataIC50: 734nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350109(US10208043, # 10 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 807nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350109(US10208043, # 10 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 807nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350110(US10208043, # 11 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 890nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350110(US10208043, # 11 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 890nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350120(US10208043, # 21 | 5-(3-chlorobenzyl)-1-(2- hydrox...)
Affinity DataIC50: 1.20E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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