Report error Found 9172 Enz. Inhib. hit(s) with Target = 'Genome polyprotein'
Affinity DatapH: 7.0 T: 2°CAssay Description:The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th...More data for this Ligand-Target Pair
Affinity DatapH: 7.0 T: 2°CAssay Description:The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th...More data for this Ligand-Target Pair
Affinity DatapH: 7.0 T: 2°CAssay Description:The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th...More data for this Ligand-Target Pair
Affinity DatapH: 7.0 T: 2°CAssay Description:The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th...More data for this Ligand-Target Pair
Affinity DatapH: 7.0 T: 2°CAssay Description:The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th...More data for this Ligand-Target Pair
Affinity DatapH: 7.0 T: 2°CAssay Description:The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th...More data for this Ligand-Target Pair
Affinity DataKd: 1.50E+4nMpH: 7.5 T: 2°CAssay Description:Binding was also measured by a competition assay with a noncovalently bound inhibitor (Kd=4.6 uM) that quenched tryptophan fluorescence upon binding ...More data for this Ligand-Target Pair
Affinity DataKd: 1.60E+4nMpH: 7.5 T: 2°CAssay Description:Binding was also measured by a competition assay with a noncovalently bound inhibitor (Kd=4.6 uM) that quenched tryptophan fluorescence upon binding ...More data for this Ligand-Target Pair
TargetGenome polyprotein [1658-1692](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Astex Pharmaceuticals
Astex Pharmaceuticals
Affinity DataKd: 22nMT: 2°CAssay Description:The protease activity of the full-length NS3-NS4a and the protease domain were measured using a FRET-based assay using a peptide substrate derived fr...More data for this Ligand-Target Pair
TargetGenome polyprotein [1658-1692](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Astex Pharmaceuticals
Astex Pharmaceuticals
Affinity DataKd: 2.40E+4nMT: 2°CAssay Description:The protease activity of the full-length NS3-NS4a and the protease domain were measured using a FRET-based assay using a peptide substrate derived fr...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0580nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 59nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 1.48nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 197nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 197nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 0.950nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMT: 2°CAssay Description:HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v...More data for this Ligand-Target Pair
