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Report error Found 584 Enz. Inhib. hit(s) with Target = 'Lanosterol synthase'
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494940(CHEMBL3098189)
Affinity DataKi:  0.600nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494929(CHEMBL3098184)
Affinity DataKi:  3nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494941(CHEMBL3098187)
Affinity DataKi:  5.60nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494943(CHEMBL3098188)
Affinity DataKi:  13nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19267(CHEMBL392204 | Mycophenolic Adenine Dinucleotide (...)
Affinity DataKi:  16nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494909(CHEMBL3098183)
Affinity DataKi:  19nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003025(1-((4aS,5S,6S,8aS)-6-Hydroxy-5,8a-dimethyl-octahyd...)
Affinity DataKi:  28nMAssay Description:Inhibitory concentration of the compound against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494933(CHEMBL3098168)
Affinity DataKi:  32nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50055641(2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...)
Affinity DataKi:  37nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494944(CHEMBL3098163)
Affinity DataKi:  38nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494913(CHEMBL3098179)
Affinity DataKi:  39nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494942(CHEMBL3098169)
Affinity DataKi:  56nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494927(CHEMBL3098165)
Affinity DataKi:  56nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494911(CHEMBL3098190)
Affinity DataKi:  63nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494912(CHEMBL3098192)
Affinity DataKi:  70nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494906(CHEMBL3098191)
Affinity DataKi:  82nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50282635((1R,7R,9aS)-7-Decyl-octahydro-quinolizin-1-ol | CH...)
Affinity DataKi:  110nMAssay Description:Evaluated for its activity to inhibit rat liver 2,3-oxidosqualene-lanosterol cyclase, activity expressed as KiMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494921(CHEMBL2437272)
Affinity DataKi:  132nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494934(CHEMBL3098167)
Affinity DataKi:  144nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494939(CHEMBL3098180)
Affinity DataKi:  163nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494919(CHEMBL3098166)
Affinity DataKi:  164nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50055642(2,2-Dimethyl-3-[(3E,7E,11E)-3,7,12-trimethyl-15-(4...)
Affinity DataKi:  180nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494936(CHEMBL3098186)
Affinity DataKi:  259nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494923(CHEMBL3098185)
Affinity DataKi:  259nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494917(CHEMBL3098182)
Affinity DataKi:  265nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19265(C2-Mycophenolic Adenine Dinucleotide (C2-MDA) | CH...)
Affinity DataKi:  300nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051375((6S,8aS)-5,5,8a-Trimethyl-2-((E)-1,5,9-trimethyl-d...)
Affinity DataKi:  300nMAssay Description:Binding affinity towards competitive inhibition against rat microsomal Oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051375((6S,8aS)-5,5,8a-Trimethyl-2-((E)-1,5,9-trimethyl-d...)
Affinity DataKi:  400nMAssay Description:Binding affinity towards noncompetetive inhibition against rat microsomal Oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494910(CHEMBL3098178)
Affinity DataKi:  491nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50055643(2,2-Dimethyl-3-[(E)-3-methyl-7-((3E,7E)-4,8,12-tri...)
Affinity DataKi:  500nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50282634((1R,7S,9aS)-7-Decyl-octahydro-quinolizin-1-ol | CH...)
Affinity DataKi:  510nMAssay Description:Evaluated for its activity to inhibit rat liver 2,3-oxidosqualene-lanosterol cyclase, activity expressed as KiMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494938(CHEMBL2437258)
Affinity DataKi:  522nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494915(CHEMBL3098164)
Affinity DataKi:  733nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494937(CHEMBL2437254)
Affinity DataKi:  854nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494930(CHEMBL3098177)
Affinity DataKi:  876nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494916(CHEMBL2437269)
Affinity DataKi:  892nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494926(CHEMBL3098176)
Affinity DataKi:  906nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494932(CHEMBL3098172)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50055642(2,2-Dimethyl-3-[(3E,7E,11E)-3,7,12-trimethyl-15-(4...)
Affinity DataKi:  1.40E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50055641(2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...)
Affinity DataKi:  1.50E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494907(CHEMBL3098171)
Affinity DataKi:  1.68E+3nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494945(CHEMBL3098170)
Affinity DataKi:  1.83E+3nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494928(CHEMBL2437273)
Affinity DataKi:  2.04E+3nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494931(CHEMBL3098174)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50055644(2-Methyl-3-((7E,11E,15Z)-3,7,12,20-tetramethyl-16-...)
Affinity DataKi:  2.50E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290988(2,2-Dimethyl-3-(3,7,12,20-tetramethyl-16-vinyl-hen...)
Affinity DataKi:  2.50E+3nMAssay Description:Compound was evaluated for the binding affinity against rat liver oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494925(CHEMBL3098181)
Affinity DataKi:  2.55E+3nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494914(CHEMBL3098173)
Affinity DataKi:  2.81E+3nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494908(CHEMBL2437261)
Affinity DataKi:  3.77E+3nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50494935(CHEMBL2437255)
Affinity DataKi:  4.31E+3nMAssay Description:Inhibition of IMPDH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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