Report error Found 670 Enz. Inhib. hit(s) with Target = 'Lysosomal alpha-glucosidase'
Affinity DataEC50: 9.88E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 7.45E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 1.18E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 4.77E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 5.84E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 6.97E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 6.53E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 1.04E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 3.72E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 4.68E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 2.10E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 1.21E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 7.71E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 6.65E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 6.60E+3nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 1.73E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 7.00E+3nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Affinity DataEC50: 2.81E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
TargetLysosomal alpha-glucosidase(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKd: 2.00E+4nMAssay Description:Binding affinity at wild type recombinant NT-495 labelled GAA incubated for 15 mins by microscale thermophoresis assayMore data for this Ligand-Target Pair
TargetLysosomal alpha-glucosidase(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKd: 2.00E+4nMAssay Description:Binding affinity at wild type recombinant NT-495 labelled GAA incubated for 15 mins by microscale thermophoresis assayMore data for this Ligand-Target Pair
TargetLysosomal alpha-glucosidase(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory activity was determined against baker's yeast Alpha-GlucosidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity measured against alpha-glucosidase of rat intestinal sucrase by colorimetric assay using the D-glucose oxidase-peroxidase methodMore data for this Ligand-Target Pair
TargetLysosomal alpha-glucosidase(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
TargetLysosomal alpha-glucosidase(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of rat intestinal brush border membrane maltaseMore data for this Ligand-Target Pair
TargetLysosomal alpha-glucosidase(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human lysosomal alpha glucosidaseMore data for this Ligand-Target Pair
TargetLysosomal alpha-glucosidase(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of lysosomal alpha-glucosidase by HPLCMore data for this Ligand-Target Pair
TargetLysosomal alpha-glucosidase(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of rat intestinal brush border membrane maltaseMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of rat intestinal brush border membrane maltaseMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
TargetLysosomal alpha-glucosidase(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:The rhGAA enzyme sold under the name Myozyme used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, t...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of Wistar rat small intestine maltase after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibitory activity measured against alpha-glucosidase of rat intestinal sucrase by colorimetric assay using the D-glucose oxidase-peroxidase methodMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of Wistar rat small intestine maltase after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of rat intestinal maltase assessed as release of D-glucose using maltose as substrate by colorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of Wistar rat small intestine maltase after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of rat small intestinal maltase after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of maltase in rat small intestinal brush border membrane vesicles using maltose as substrate incubated for 30 mins by glucose-oxidase meth...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
