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Report error Found 2295 Enz. Inhib. hit(s) with Target = 'Methionine aminopeptidase'
LigandPNGBDBM17451(5-(4-methylphenyl)-1H-pyrazole | pyrazole analogue...)
Affinity DatapH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandPNGBDBM36588(AGM-1470)
Affinity DataEC50:  0.0370nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandPNGBDBM36589(Ovalicin)
Affinity DataEC50:  0.0180nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandPNGBDBM36590(FOS-72)
Affinity DataEC50:  0.0130nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandPNGBDBM36595(FOS-68)
Affinity DataEC50:  0.460nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandPNGBDBM36597(FOS-69)
Affinity DataEC50:  0.310nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandPNGBDBM36592(FOS-70)
Affinity DataEC50:  0.120nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandPNGBDBM36591(FOS-37)
Affinity DataEC50:  9.5nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandPNGBDBM36596(FOS-34)
Affinity DataEC50:  2.20nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandPNGBDBM36593(FOS-64)
Affinity DataEC50:  110nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandPNGBDBM36598(FOS-67)
Affinity DataEC50:  40nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandPNGBDBM36599(FOS-201)
Affinity DataEC50:  56nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandPNGBDBM36594(FOS-202)
Affinity DataEC50:  2.80E+3nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50433373(CHEMBL2375609)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50433374(CHEMBL2375610)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50121347(CHEMBL625 | THIABENDAZOLE)
Affinity DataEC50:  3.40E+3nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50042874(2,2'-bipyridine | 2,2'-Bipyridin | 2,2'-bipyridyl ...)
Affinity DataEC50:  320nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM17847(tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...)
Affinity DataEC50:  350nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433375(GNF-Pf-359 | CHEMBL472879)
Affinity DataEC50:  190nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433376(CHEMBL2375627)
Affinity DataEC50:  430nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433377(CHEMBL2375628)
Affinity DataEC50:  280nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433378(CHEMBL2375629)
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM47468(N-(2-phenylethyl)-2-(2-pyridinyl)-4-quinazolinamin...)
Affinity DataEC50:  940nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433379(CHEMBL2375611)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433380(CHEMBL2375612)
Affinity DataEC50:  120nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433381(CHEMBL2375613)
Affinity DataEC50:  110nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433382(CHEMBL1329554)
Affinity DataEC50:  49nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433383(CHEMBL2375614)
Affinity DataEC50:  390nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433384(CHEMBL45721)
Affinity DataEC50:  410nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433385(CHEMBL49678)
Affinity DataEC50:  870nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433386(CHEMBL2375615)
Affinity DataEC50:  73nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433387(CHEMBL2375616)
Affinity DataEC50:  94nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433388(CHEMBL2375617)
Affinity DataEC50:  900nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433389(CHEMBL2375618)
Affinity DataEC50:  180nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433390(CHEMBL2375619)
Affinity DataEC50:  6.00E+3nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433391(CHEMBL2375620)
Affinity DataEC50:  94nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433392(CHEMBL2375621)
Affinity DataEC50:  110nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433393(CHEMBL2375622)
Affinity DataEC50:  81nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433394(CHEMBL2375623)
Affinity DataEC50:  590nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433395(CHEMBL2375624)
Affinity DataEC50:  100nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433396(CHEMBL2375625)
Affinity DataEC50:  850nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433397(CHEMBL2375626)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433398(CHEMBL2375607)
Affinity DataEC50:  390nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433399(CHEMBL2375608)
Affinity DataEC50:  250nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433373(CHEMBL2375609)
Affinity DataEC50:  93nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433374(CHEMBL2375610)
Affinity DataEC50:  120nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50121347(CHEMBL625 | THIABENDAZOLE)
Affinity DataEC50: >2.50E+5nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Zn2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50042874(2,2'-bipyridine | 2,2'-Bipyridin | 2,2'-bipyridyl ...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Zn2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM17847(tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Zn2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50433375(GNF-Pf-359 | CHEMBL472879)
Affinity DataEC50:  710nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Zn2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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