Report error Found 193 Enz. Inhib. hit(s) with Target = 'Parathyroid hormone/parathyroid hormone-related peptide receptor'
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataEC50: 2.40E+3nMpH: 7.4Assay Description:Instead of HKRK-B7 cells, LLC-PK46_RATO_PTH1R cells overexpressing rat PTH1R, which were established at Chugai Pharmaceutical, were used to take meas...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataEC50: 1.90E+3nMpH: 7.4Assay Description:Instead of HKRK-B7 cells, LLC-PK46_RATO_PTH1R cells overexpressing rat PTH1R, which were established at Chugai Pharmaceutical, were used to take meas...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataEC50: 1.20E+4nMpH: 7.4Assay Description:Instead of HKRK-B7 cells, LLC-PK46_RATO_PTH1R cells overexpressing rat PTH1R, which were established at Chugai Pharmaceutical, were used to take meas...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataEC50: 3.20E+3nMpH: 7.4Assay Description:Instead of HKRK-B7 cells, LLC-PK46_RATO_PTH1R cells overexpressing rat PTH1R, which were established at Chugai Pharmaceutical, were used to take meas...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataEC50: 2.30E+3nMpH: 7.4Assay Description:Instead of HKRK-B7 cells, LLC-PK46_RATO_PTH1R cells overexpressing rat PTH1R, which were established at Chugai Pharmaceutical, were used to take meas...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKd: 21.6nMAssay Description:Binding affinity to PTH/PTH-related peptide receptor expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 26nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 32nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 800nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formationMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataEC50: 155nMAssay Description:Activity at rat PTH/PTH-related peptide receptor expressed in rat UMR106 cells assessed as cAMP formationMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 7.20nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formationMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formationMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 2.20nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formationMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.43E+3nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formationMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.46E+3nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formationMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formationMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataEC50: 1.10nMAssay Description:Activity at rat PTH/PTH-related peptide receptor expressed in rat UMR106 cells assessed as cAMP formationMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataEC50: 344nMAssay Description:Activity at rat PTH/PTH-related peptide receptor expressed in rat UMR106 cells assessed as cAMP formationMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataEC50: 129nMAssay Description:Activity at rat PTH/PTH-related peptide receptor expressed in rat UMR106 cells assessed as cAMP formationMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataEC50: 251nMAssay Description:Activity at rat PTH/PTH-related peptide receptor expressed in rat UMR106 cells assessed as cAMP formationMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.920nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.150nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.0600nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 13nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 26nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 53nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at PTH1R overexpressed in HEK293 cells assessed as intracellular cAMP productionMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at PTH1R overexpressed in HEK293 cells assessed as intracellular cAMP mobilizationMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 3.20E+3nMAssay Description:Agonist activity at PTH1R overexpressed in HEK293 cells assessed as intracellular cAMP mobilizationMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.12E+3nMAssay Description:Agonist activity at recombinant PTHR1 expressed in HEK293 cells co-transfected with CRE-Luc assessed as increase of adenylyl cyclase activity after 4...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at recombinant PTHR1 expressed in HEK293 cells co-transfected with CRE-Luc assessed as increase of adenylyl cyclase activity after 4...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 2.40nMAssay Description:Agonist activity at recombinant PTHR1 expressed in HEK293 cells co-transfected with CRE-Luc assessed as increase of adenylyl cyclase activity after 4...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.440nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.400nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.340nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 167nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.260nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.170nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.140nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 9.70nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.340nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.170nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.150nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 2.60nMAssay Description:Agonist activity at human PTH1 receptor expressed in human GP2.3 cells assessed as induction of cAMP after 12 to 20 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
