Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with Target = 'Peptidoglycan D,D-transpeptidase MrdA'
LigandPNGBDBM708193(US12173018, Example 121)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708159(US12173018, Example 87)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708161(US12173018, Example 89)
Affinity DataEC50:  2.65E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708162(US12173018, Example 90)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708173(US12173018, Example 101)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708174(US12173018, Example 102)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708175(US12173018, Example 103)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708176(US12173018, Example 104)
Affinity DataEC50:  2.65E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708181(US12173018, Example 109)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708182(US12173018, Example 110)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708186(US12173018, Example 114)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708189(US12173018, Example 117)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708154(US12173018, Example 81)
Affinity DataEC50:  2.65E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708198(US12173018, Example 126)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708203(US12173018, Example 131)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708207(US12173018, Example 135)
Affinity DataEC50:  2.65E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708210(US12173018, Example 138)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708214(US12173018, Example 142)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708220(US12173018, Example 148)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708222(US12173018, Example 150)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708223(US12173018, Example 151)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708226(US12173018, Example 154)
Affinity DataEC50:  2.65E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708228(US12173018, Example 156)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708135(US12173018, Example 51)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708119(US12173018, Example 34)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708115(US12173018, Example 27)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708109(US12173018, Example 20)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708106(US12173018, Example 16)
Affinity DataEC50: >5.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708306(US12173018, Example 5)
Affinity DataEC50:  2.65E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50512952(CHEMBL4560540)
Affinity DataIC50: 10nMAssay Description:Inhibition of bocillin-FL binding to Escherichia coli K12 NusA-fused/His6-tagged PBP2 (57 to 615 residues) expressed in Escherichia coli BL21(DE3) pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50512949(CHEMBL4470489)
Affinity DataIC50: 17nMAssay Description:Inhibition of bocillin-FL binding to Escherichia coli K12 NusA-fused/His6-tagged PBP2 (57 to 615 residues) expressed in Escherichia coli BL21(DE3) pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50512948(CHEMBL4476279)
Affinity DataIC50: 25nMAssay Description:Inhibition of bocillin-FL binding to Escherichia coli K12 NusA-fused/His6-tagged PBP2 (57 to 615 residues) expressed in Escherichia coli BL21(DE3) pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50213266(CHEBI:471744 | Imipenem | MK-0787)
Affinity DataIC50: 33.4nMAssay Description:Inhibition of bocillin FL binding to Escherichia coli MC4100 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Pseudomonas aeruginosa)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213266(CHEBI:471744 | Imipenem | MK-0787)
Affinity DataIC50: 334nMAssay Description:Inhibition of bocillin FL binding to Pseudomonas aeruginosa PAO1 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50103601(CHEBI:29007 | Ceftriaxone)
Affinity DataIC50: 360nMAssay Description:Inhibition of bocillin FL binding to Escherichia coli MC4100 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50378857(Zeftera | Zevtera | CEFTOBIPROLE)
Affinity DataIC50: 374nMAssay Description:Inhibition of bocillin FL binding to Escherichia coli MC4100 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50512953(CHEMBL4515223)
Affinity DataIC50: 570nMAssay Description:Inhibition of bocillin-FL binding to Escherichia coli K12 NusA-fused/His6-tagged PBP2 (57 to 615 residues) expressed in Escherichia coli BL21(DE3) pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50512951(CHEBI:85982 | Avibactam sodium | Nxl-104)
Affinity DataIC50: 590nMAssay Description:Inhibition of bocillin-FL binding to Escherichia coli K12 NusA-fused/His6-tagged PBP2 (57 to 615 residues) expressed in Escherichia coli BL21(DE3) pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50350470(Maxipime | CEFEPIME)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of bocillin FL binding to Escherichia coli MC4100 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Pseudomonas aeruginosa)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50378857(Zeftera | Zevtera | CEFTOBIPROLE)
Affinity DataIC50: 5.61E+3nMAssay Description:Inhibition of bocillin FL binding to Pseudomonas aeruginosa PAO1 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50420259(CEFTAZIDIME)
Affinity DataIC50: 7.31E+3nMAssay Description:Inhibition of bocillin FL binding to Escherichia coli MC4100 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Pseudomonas aeruginosa)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50350470(Maxipime | CEFEPIME)
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of bocillin FL binding to Pseudomonas aeruginosa PAO1 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50240480(CHEMBL158 | (2S,3S)-3-({(2Z)-2-(2-ammonio-1,3-thia...)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of bocillin FL binding to Escherichia coli MC4100 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Pseudomonas aeruginosa)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50240480(CHEMBL158 | (2S,3S)-3-({(2Z)-2-(2-ammonio-1,3-thia...)
Affinity DataIC50: 3.67E+4nMAssay Description:Inhibition of bocillin FL binding to Pseudomonas aeruginosa PAO1 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Pseudomonas aeruginosa)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50420259(CEFTAZIDIME)
Affinity DataIC50: 5.85E+4nMAssay Description:Inhibition of bocillin FL binding to Pseudomonas aeruginosa PAO1 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50512950(CHEMBL4545278)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of bocillin-FL binding to Escherichia coli K12 NusA-fused/His6-tagged PBP2 (57 to 615 residues) expressed in Escherichia coli BL21(DE3) pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed