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Report error Found 345 Enz. Inhib. hit(s) with Target = 'Phospho-N-acetylmuramoyl-pentapeptide-transferase'
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Bacillus subtilis (strain 168))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50343928(CHEMBL1780216 | Muraymycin D2)
Affinity DataKi:  7.60nMAssay Description:Competitive inhibition of Bacillus subtilis MraY using UDP-MurNAc-pentapeptide as substrate after 30 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Bacillus subtilis (strain 168))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50343928(CHEMBL1780216 | Muraymycin D2)
Affinity DataKi:  7.60nMAssay Description:Noncompetitive inhibition of Bacillus subtilis MraY using radiolabeled UDP-GlcNAc as substrate after 30 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Bacillus subtilis (strain 168))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50343929((2S,6S,9R,16S)-16-((S)-((2S,3R,4S,5R)-5-(aminometh...)
Affinity DataKi:  49nMAssay Description:Competitive inhibition of Bacillus subtilis MraY using UDP-MurNAc-pentapeptide as substrate after 30 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Bacillus subtilis (strain 168))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50343929((2S,6S,9R,16S)-16-((S)-((2S,3R,4S,5R)-5-(aminometh...)
Affinity DataKi:  49nMAssay Description:Noncompetitive inhibition of Bacillus subtilis MraY using radiolabeled UDP-GlcNAc as substrate after 30 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Bacillus subtilis (strain 168))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50343930((2S,6S,9S,16S)-16-((S)-((2S,3R,4S,5R)-5-(aminometh...)
Affinity DataKi:  247nMAssay Description:Noncompetitive inhibition of Bacillus subtilis MraY using radiolabeled UDP-GlcNAc as substrate after 30 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Bacillus subtilis (strain 168))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50343930((2S,6S,9S,16S)-16-((S)-((2S,3R,4S,5R)-5-(aminometh...)
Affinity DataKi:  247nMAssay Description:Competitive inhibition of Bacillus subtilis MraY using UDP-MurNAc-pentapeptide as substrate after 30 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Bacillus subtilis (strain 168))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50343931((2S,6S,9R,16S)-16-((S)-((2S,3R,4S,5R)-5-(aminometh...)
Affinity DataKi:  698nMAssay Description:Noncompetitive inhibition of Bacillus subtilis MraY using radiolabeled UDP-GlcNAc as substrate after 30 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Bacillus subtilis (strain 168))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50343931((2S,6S,9R,16S)-16-((S)-((2S,3R,4S,5R)-5-(aminometh...)
Affinity DataKi:  698nMAssay Description:Competitive inhibition of Bacillus subtilis MraY using UDP-MurNAc-pentapeptide as substrate after 30 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Staphylococcus aureus)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50465326(CHEMBL4283345)
Affinity DataIC50:  0.00400nMAssay Description:Inhibition of Staphylococcus aureus MraY expressed in Escherichia coli membrane using Park's nucleotide as substrate pretreated for 30 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Aquifex aeolicus (strain VF5))
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50465326(CHEMBL4283345)
Affinity DataIC50:  0.00700nMAssay Description:Inhibition of Aquifex aeolicus MraY expressed in Escherichia coli C41(DE3) using Park's nucleotide as substrate pretreated for 30 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Staphylococcus aureus)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50465324(CHEMBL4286766)
Affinity DataIC50:  0.0160nMAssay Description:Inhibition of Staphylococcus aureus MraY expressed in Escherichia coli membrane using Park's nucleotide as substrate pretreated for 30 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Staphylococcus aureus)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50465327(CHEMBL4279378)
Affinity DataIC50:  0.0220nMAssay Description:Inhibition of Staphylococcus aureus MraY expressed in Escherichia coli membrane using Park's nucleotide as substrate pretreated for 30 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Staphylococcus aureus)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50465325(CHEMBL4284923)
Affinity DataIC50:  0.0930nMAssay Description:Inhibition of Staphylococcus aureus MraY expressed in Escherichia coli membrane using Park's nucleotide as substrate pretreated for 30 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Aquifex aeolicus (strain VF5))
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50465327(CHEMBL4279378)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of Aquifex aeolicus MraY expressed in Escherichia coli C41(DE3) using Park's nucleotide as substrate pretreated for 30 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Aquifex aeolicus (strain VF5))
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50465324(CHEMBL4286766)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of Aquifex aeolicus MraY expressed in Escherichia coli C41(DE3) using Park's nucleotide as substrate pretreated for 30 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Aquifex aeolicus (strain VF5))
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50465325(CHEMBL4284923)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of Aquifex aeolicus MraY expressed in Escherichia coli C41(DE3) using Park's nucleotide as substrate pretreated for 30 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Staphylococcus aureus)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50526643(CHEMBL4475677)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of MraY in Staphylococcus aureusMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50614445(CHEMBL5282738)
Affinity DataIC50:  10nMAssay Description:Inhibition of MraY in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Bacillus subtilis (strain 168))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50343928(CHEMBL1780216 | Muraymycin D2)
Affinity DataIC50:  10nMAssay Description:Inhibition of Bacillus subtilis MraY using radiolabeled UDP-MurNAc-[14C]pentapeptide as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Bacillus subtilis (strain 168))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50343928(CHEMBL1780216 | Muraymycin D2)
Affinity DataIC50:  10nMAssay Description:Inhibition of purified Bacillus subtilis MraY assessed as incorporation of MurNAc-[14C]pentapeptide into lipid 1 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50465328(CHEMBL4283943)
Affinity DataIC50:  11nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv MraY expressed in Mycobacterium smegmatis using Park's nucleotide-N-epsilon-C6-dansyl as substrate mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221211(CHEMBL97077)
Affinity DataIC50:  12.2nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221211(CHEMBL97077)
Affinity DataIC50:  12.2nMAssay Description:Inhibitory concentration required against Translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221473(CHEMBL94424)
Affinity DataIC50:  13.9nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221201(CHEMBL97712)
Affinity DataIC50:  15.8nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Staphylococcus aureus)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50614429(CHEMBL5265940)
Affinity DataIC50:  17nMAssay Description:Inhibition of Staphylococcus aureus MraYMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50135598((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50135598((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50135598((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)
Affinity DataIC50:  17.1nMAssay Description:Inhibitory concentration against translocase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50135599((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)
Affinity DataIC50:  17.6nMAssay Description:Inhibitory concentration against translocase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50135599((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50135599((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221409(CHEMBL96162)
Affinity DataIC50:  18.1nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Staphylococcus aureus)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50386961(CHEMBL2048825)
Affinity DataIC50:  22nMAssay Description:Inhibition of Staphylococcus aureus MraY using UDP-MurNAc-dansylpentapeptide substrate assessed as formation of dansylated lipid I incubated for 3 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Bacillus subtilis (strain 168))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50614433(CHEMBL5272467)
Affinity DataIC50:  22nMAssay Description:Inhibition of Bacillus subtilis MraYMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Staphylococcus aureus)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50386963(CHEMBL2048828)
Affinity DataIC50:  22nMAssay Description:Inhibition of Staphylococcus aureus MraY using UDP-MurNAc-dansylpentapeptide substrate assessed as formation of dansylated lipid I incubated for 3 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221204(CHEMBL327358)
Affinity DataIC50:  22.8nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221205(CHEMBL317088)
Affinity DataIC50:  22.9nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221054(CHEMBL97606)
Affinity DataIC50:  23.7nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Staphylococcus aureus)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50526632(CHEMBL4473600)
Affinity DataIC50:  24nMAssay Description:Inhibition of MraY in Staphylococcus aureusMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Staphylococcus aureus)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50526632(CHEMBL4473600)
Affinity DataIC50:  24nMAssay Description:Inhibition of MraY in Staphylococcus aureusMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221475(CHEMBL94839)
Affinity DataIC50:  25.1nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221469(CHEMBL329448)
Affinity DataIC50:  26.3nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Staphylococcus aureus)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50614430(CHEMBL5277590)
Affinity DataIC50:  27nMAssay Description:Inhibition of Staphylococcus aureus MraYMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221051(CHEMBL319731)
Affinity DataIC50:  30.1nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221457(CHEMBL94400)
Affinity DataIC50:  31.6nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221331(CHEMBL430672)
Affinity DataIC50:  32.1nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221407(CHEMBL418960)
Affinity DataIC50:  32.6nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221408(CHEMBL97276)
Affinity DataIC50:  33.2nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50221330(CHEMBL96561)
Affinity DataIC50:  33.5nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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