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Report error Found 1906 Enz. Inhib. hit(s) with Target = 'Polyphenol oxidase 2'
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534033(CHEMBL4473153)
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534034(CHEMBL4464052)
Affinity DataEC50:  3.00E+3nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534035(CHEMBL4470012)
Affinity DataEC50:  5.60E+3nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534036(CHEMBL4462337)
Affinity DataEC50:  1.46E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534037(CHEMBL4440265)
Affinity DataEC50:  1.71E+3nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534038(CHEMBL4592732)
Affinity DataEC50:  3.74E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534039(CHEMBL4473442)
Affinity DataEC50:  1.71E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534040(CHEMBL4468479)
Affinity DataEC50:  3.06E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534041(CHEMBL4559940)
Affinity DataEC50:  2.11E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534042(CHEMBL4469461)
Affinity DataEC50:  5.62E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534043(CHEMBL4446279)
Affinity DataEC50:  3.56E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534044(CHEMBL4548215)
Affinity DataEC50:  2.89E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534045(CHEMBL4567344)
Affinity DataEC50:  2.55E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534046(CHEMBL4594133)
Affinity DataEC50:  4.72E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534047(CHEMBL4581303)
Affinity DataEC50:  1.27E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534048(CHEMBL4545495)
Affinity DataEC50:  8.10E+3nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534049(CHEMBL4453720)
Affinity DataEC50:  2.38E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534050(CHEMBL4475422)
Affinity DataEC50:  1.30E+3nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534051(CHEMBL4522700)
Affinity DataEC50:  6.40E+3nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534052(CHEMBL4469401)
Affinity DataEC50:  9.60E+3nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534053(CHEMBL3409828)
Affinity DataEC50:  2.58E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534054(CHEMBL4463325)
Affinity DataEC50:  1.14E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534055(CHEMBL4522932)
Affinity DataEC50:  6.53E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534056(CHEMBL4466784)
Affinity DataEC50:  2.13E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534057(CHEMBL4542422)
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534058(CHEMBL4462990)
Affinity DataEC50:  2.39E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534059(CHEMBL4471626)
Affinity DataEC50:  7.81E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50041234(9-methoxy-7H-furo[3,2-g]chromen-7-one | CHEMBL416 ...)
Affinity DataEC50:  1.48E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534060(CHEMBL4465047)
Affinity DataEC50:  2.50E+3nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534061(CHEMBL4460236)
Affinity DataEC50:  1.19E+4nMAssay Description:Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM110191(3-(2,4-Dihydroxyphenyl)-1-(thiophen-2-yl)propenone...)
Affinity DataIC50: 0.0130nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as diphenolase activity incubated for 20 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM110192(3-(2,4-Dihydroxyphenyl)-1-(furan-2-yl)propenone (1...)
Affinity DataIC50: 0.0433nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as diphenolase activityMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50608336(CHEMBL517832)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 10 mins by spectrophotometer assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50356191(CHEMBL193804)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as monophenolase activity preincubated for 20 mins followed by substrate add...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50610779(CHEMBL4475728)
Affinity DataIC50: 0.0680nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as a substrate by UV-2450 spectrophotometeric assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50276368(CHEMBL4128371)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microti...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50610793(CHEMBL5286240)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microti...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50610794(CHEMBL5286802)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microti...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50610795(CHEMBL5289108)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microti...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50610775(CHEMBL5277673)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microti...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM110192(3-(2,4-Dihydroxyphenyl)-1-(furan-2-yl)propenone (1...)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as monophenolase activityMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50610778(CHEMBL4562624)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as a substrate by UV-2450 spectrophotometeric assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50610783(CHEMBL4064477)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50045000(CHEMBL9 | (norfloxacin)1-Ethyl-6-fluoro-4-oxo-7-pi...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM110191(3-(2,4-Dihydroxyphenyl)-1-(thiophen-2-yl)propenone...)
Affinity DataIC50: 0.930nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as monophenolase activity incubated for 20 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50208612(kurarinone | (-)-kurarinone | (2S)-2-(2,4-dihydrox...)
Affinity DataIC50: 0.960nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 10 mins by spectrophotometer assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50366824(Avelox | MOXIFLOXACIN | Moxifl-oxacin)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50609374(CHEMBL5274383)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate incubated for 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50234121(CHEMBL4069921)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated with compound for 20 mins measured after 1 minMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50610789(CHEMBL5284672)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
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