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Report error Found 510 Enz. Inhib. hit(s) with Target = 'Protein kinase C zeta type'
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50505541(CHEMBL4465866)
Affinity DataKd:  1.25E+3nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PRKCZ (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50505542(CHEMBL4576489)
Affinity DataKd:  1.35E+3nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PRKCZ (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50175688((4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)p...)
Affinity DataEC50:  3nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM139468(US8889672, 317-054-001)
Affinity DataEC50:  10nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM139466(US8889672, 317-094-001)
Affinity DataEC50:  1nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM139469(US8889672, 317-052-004)
Affinity DataEC50:  1nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM139465(US8889672, 317-080-001)
Affinity DataEC50:  1nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM139472(US8889672, 252-036-001)
Affinity DataEC50:  2nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM139464(US8889672, 194-074-007 | US8889672, PKCzI-diMeO)
Affinity DataEC50:  3nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM139467(US8889672, 268-020-002)
Affinity DataEC50:  2nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542127(CHEMBL4635482)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542127(CHEMBL4635482)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFKC as substrate measured by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542123(CHEMBL4636488)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542116(CHEMBL4646995)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542119(CHEMBL4644939)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542128(CHEMBL4636337)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542132(CHEMBL4632523)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50468260(CHEMBL4282837)
Affinity DataIC50: 1nMAssay Description:Inhibition of rat brain PKC using RGFR derived peptide substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542133(CHEMBL4643553)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542126(CHEMBL4642166)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542129(CHEMBL4637452)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50469649(CHEMBL283259)
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of protein kinase C from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article

TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35167(indazole-benzimidazole, 3)
Affinity DataIC50: 2.26nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50469642(CHEMBL282805)
Affinity DataIC50: 2.40nMAssay Description:In vitro inhibition of protein kinase C from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article

TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50469642(CHEMBL282805)
Affinity DataIC50: 2.40nMAssay Description:In vitro inhibition of protein kinase C from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article

TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 3nMAssay Description:Inhibition of protein kinase CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542134(CHEMBL4647780)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542125(CHEMBL4643470)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50469644(CHEMBL281448)
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of protein kinase C from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article

TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35173(indazole-benzimidazole, 9)
Affinity DataIC50: 5.18nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35168(indazole-benzimidazole, 4)
Affinity DataIC50: 5.60nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of protein kinase C from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article

TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542121(CHEMBL4641918)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50469655(CHEMBL26872)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of protein kinase C from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article

TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542130(CHEMBL4632384)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 10nMAssay Description:Inhibition of protein kinase CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50469652(CHEMBL285613)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of protein kinase C from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article

TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50455589(CHEMBL4213984)
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-zeta expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50469643(CHEMBL284632)
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of protein kinase C from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article

TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50543625(CHEMBL3732444)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant full-length human aPKCzeta expressed in Sf21 insect cells using 5FAM-ERMRPRKRQGSVRRRV-NH2 as substrate in presence of ATP a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542111(CHEMBL4644763)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542122(CHEMBL4642061)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542111(CHEMBL4644763)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFKC as substrate measured by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50469641(CHEMBL283903)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of protein kinase C from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article

TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50469640(CHEMBL26817)
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of protein kinase C from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article

TargetProtein kinase C zeta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542131(CHEMBL4634517)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50469645(CHEMBL26074)
Affinity DataIC50: 17nMAssay Description:In vitro inhibition of protein kinase C from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article

TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50478518(CHEMBL514017)
Affinity DataIC50: 17nMAssay Description:Displacement of [3H]PDBu from rat brain membrane PKCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50469646(CHEMBL27387)
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of protein kinase C from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article

TargetProtein kinase C zeta type(Rat)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50469639(CHEMBL282298)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of protein kinase C from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article

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