Compile Data Set for Download or QSAR
Report error Found 5087 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 5 subunit alpha'
TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM168436(US9675591, SKA-19)
Affinity DataEC50:  5.80E+3nMpH: 7.35 T: 2°CAssay Description:All experiments were conducted at room temperature (22-24° C.) with an EPC-10 amplifier and Pulse software (HEKA, Lambrecht/Pfalz, Germany) in the wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50505257(CHEMBL4471012)
Affinity DataKd:  460nMAssay Description:Binding affinity to human recombinant Nav1.5 by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM76858(US9694002, 580 | US9546164, 580)
Affinity DataKd:  370nMAssay Description:Binding affinity to human recombinant Nav1.5 by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50521571(CHEMBL4464990)
Affinity DataKd: >1.00E+3nMAssay Description:Inhibition of full length human Nav1.5 expressed in HEK293 cells at -60 mV holding potential by manual patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50538344(CHEMBL4633246)
Affinity DataEC50: >3.30E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50546897(CHEMBL4753470)
Affinity DataEC50:  1.90nMAssay Description:Inhibition of NaV1.5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50582054(CHEMBL5091679)
Affinity DataEC50:  138nMAssay Description:Modulator activity at human Nav1.5 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50582055(CHEMBL5083412)
Affinity DataEC50:  149nMAssay Description:Modulator activity at human Nav1.5 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50582056(CHEMBL5091623)
Affinity DataEC50:  108nMAssay Description:Modulator activity at human Nav1.5 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50582057(CHEMBL5077579)
Affinity DataEC50:  28nMAssay Description:Modulator activity at human Nav1.5 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50582058(CHEMBL5093878)
Affinity DataEC50:  133nMAssay Description:Modulator activity at human Nav1.5 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50582059(CHEMBL5082582)
Affinity DataEC50:  215nMAssay Description:Modulator activity at human Nav1.5 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50582060(CHEMBL5084333)
Affinity DataEC50:  156nMAssay Description:Modulator activity at human Nav1.5 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50118519(CHEMBL3617050)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of NaV1.5 channel (unknown origin) expressed in Xenopus laevis oocytes by two-electrode oocyte voltage-clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71381(US9694002, 440 | US9546164, 440)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71340(US9694002, 411 | US9546164, 411)
Affinity DataIC50: 0.800nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71351(US9694002, 422 | US9546164, 422)
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71341(US9694002, 412 | US9546164, 412)
Affinity DataIC50: 1.5nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM70878(US9694002, 52 | US9546164, 52)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71055(US9694002, 202 | US9546164, 202)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71063(US9694002, 208 | US9546164, 208)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71101(US9694002, 236 | US9546164, 236)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71193(US9694002, 300 | US9546164, 300)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71065(US9694002, 210 | US9546164, 210)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71137(US9694002, 260 | US9546164, 260)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71062(US9694002, 207 | US9546164, 207)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71064(US9694002, 209 | US9546164, 209)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71067(US9694002, 211 | US9546164, 211)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71061(US9694002, 206 | US9546164, 206)
Affinity DataIC50: 1.80nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM70982(US9694002, 136 | US9546164, 136)
Affinity DataIC50: 1.88nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71208(US9694002, 309 | US9546164, 309)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM70876(US9694002, 51 | US9694002, 50 | US9546164, 50)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71065(US9694002, 210 | US9546164, 210)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71192(US9694002, 299 | US9546164, 299)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71222(US9694002, 322 | US9546164, 322)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71224(US9694002, 323 | US9546164, 323)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71271(US9694002, 352 | US9546164, 352)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71285(US9694002, 361 | US9546164, 361)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71006(US9694002, 155 | US9546164, 155)
Affinity DataIC50: 2.02nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM70985(US9694002, 137 | US9546164, 137)
Affinity DataIC50: 2.05nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM263408(US9546164, 42 | (R)-5-cyclopropyl-N-(cyclopropylsu...)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM263417((5-cyclopropyl-4-(((R)-1-((R)-1-(3,5-dichloropheny...)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM70946(US9694002, 107 | US9546164, 107)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71328(US9694002, 400 | US9546164, 400)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71352(US9694002, 423 | US9546164, 423)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71546(US9694002, 556 | US9546164, 556)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71107(US9694002, 238 | US9546164, 238)
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71136(US9694002, 259 | US9546164, 259)
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM71211(US9694002, 312 | US9546164, 312)
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM263861(4-(((1R,3r,5S)-3-(3-chloro-5-(trifluoromethoxy)phe...)
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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