Compile Data Set for Download or QSAR
Report error Found 348 Enz. Inhib. hit(s) with Target = 'Tissue alpha-L-fucosidase'
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072685((3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperid...)
Affinity DataIC50: 4nMAssay Description:Compound was tested for inhibitory activity against alpha-1,2-Fucosidase obtained from Arthrobacter oxidansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50065258(CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)
Affinity DataIC50: 5nMAssay Description:Inhibition of bovine alpha-L-fucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442341(CHEMBL2442786)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072685((3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperid...)
Affinity DataIC50: 11nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072685((3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperid...)
Affinity DataIC50: 11nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442341(CHEMBL2442786)
Affinity DataIC50: 12nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442339(CHEMBL2442788)
Affinity DataIC50: 14nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442344(CHEMBL2442783)
Affinity DataIC50: 15nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM394396(US10308607, Compound II)
Affinity DataIC50: 16nMAssay Description:Fucosidase inhibition was assessed by preparing a reaction mixture of 50 mM phosphate-citrate pH 4.5, 5 mM MgCl2, 640 nM 4-methylumbelliferyl-alpha-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442343(CHEMBL2442784)
Affinity DataIC50: 19nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072687((S)-2-Amino-3-hydroxy-N-(3,4,5-trihydroxy-2-hydrox...)
Affinity DataIC50: 20nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442343(CHEMBL2442784)
Affinity DataIC50: 21nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442348(CHEMBL2442779)
Affinity DataIC50: 26nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442344(CHEMBL2442783)
Affinity DataIC50: 26nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442340(CHEMBL2442787)
Affinity DataIC50: 28nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442345(CHEMBL2442782)
Affinity DataIC50: 30nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442350(CHEMBL2442777)
Affinity DataIC50: 30nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442339(CHEMBL2442788)
Affinity DataIC50: 30nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442340(CHEMBL2442787)
Affinity DataIC50: 31nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442338(CHEMBL2442773)
Affinity DataIC50: 35nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072687((S)-2-Amino-3-hydroxy-N-(3,4,5-trihydroxy-2-hydrox...)
Affinity DataIC50: 40nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072682({[(3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piper...)
Affinity DataIC50: 40nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442345(CHEMBL2442782)
Affinity DataIC50: 40nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442338(CHEMBL2442773)
Affinity DataIC50: 42nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442348(CHEMBL2442779)
Affinity DataIC50: 43nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50442341(CHEMBL2442786)
Affinity DataIC50: 44nMAssay Description:Inhibition of rat epididymis alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442346(CHEMBL2442781)
Affinity DataIC50: 47nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442350(CHEMBL2442777)
Affinity DataIC50: 47nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072684(2-Amino-N-(3,4,5-trihydroxy-2-hydroxymethyl-6-meth...)
Affinity DataIC50: 50nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072687((S)-2-Amino-3-hydroxy-N-(3,4,5-trihydroxy-2-hydrox...)
Affinity DataIC50: 56nMAssay Description:Compound was tested for inhibitory activity against alpha-1,2-Fucosidase obtained from Arthrobacter oxidans F1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442346(CHEMBL2442781)
Affinity DataIC50: 58nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM394397(US10308607, Compound III)
Affinity DataIC50: 59nMAssay Description:Fucosidase inhibition was assessed by preparing a reaction mixture of 50 mM phosphate-citrate pH 4.5, 5 mM MgCl2, 640 nM 4-methylumbelliferyl-alpha-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072683(3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperidi...)
Affinity DataIC50: 75nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072686(2-Aminomethyl-2-hydroxymethyl-6-methyl-piperidine-...)
Affinity DataIC50: 80nMAssay Description:Compound was tested for inhibitory activity against alpha-1,2-Fucosidase obtained from Arthrobacter oxidans F1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50442344(CHEMBL2442783)
Affinity DataIC50: 81nMAssay Description:Inhibition of rat epididymis alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442351(CHEMBL2442776)
Affinity DataIC50: 86nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50442339(CHEMBL2442788)
Affinity DataIC50: 100nMAssay Description:Inhibition of rat epididymis alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072683(3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperidi...)
Affinity DataIC50: 110nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50118923(4-Methyl-6-octylamino-cyclohexane-1,2,3-triol | (1...)
Affinity DataIC50: 110nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50065258(CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)
Affinity DataIC50: 110nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072684(2-Amino-N-(3,4,5-trihydroxy-2-hydroxymethyl-6-meth...)
Affinity DataIC50: 116nMAssay Description:Compound was tested for inhibitory activity against alpha-1,2-Fucosidase obtained from Arthrobacter oxidans F1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072683(3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperidi...)
Affinity DataIC50: 122nMAssay Description:Compound was tested for inhibitory activity against alpha-1,2-Fucosidase obtained from Arthrobacter oxidans F1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442347(CHEMBL2442780)
Affinity DataIC50: 130nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065258(CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065258(CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)
Affinity DataIC50: 140nMAssay Description:Inhibition of placental alpha-L-fucosidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072686(2-Aminomethyl-2-hydroxymethyl-6-methyl-piperidine-...)
Affinity DataIC50: 160nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442347(CHEMBL2442780)
Affinity DataIC50: 160nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072684(2-Amino-N-(3,4,5-trihydroxy-2-hydroxymethyl-6-meth...)
Affinity DataIC50: 170nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50442345(CHEMBL2442782)
Affinity DataIC50: 170nMAssay Description:Inhibition of rat epididymis alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50442348(CHEMBL2442779)
Affinity DataIC50: 170nMAssay Description:Inhibition of rat epididymis alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
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