Compile Data Set for Download or QSAR
Found 347 Enz. Inhib. hit(s) with Target = 'Tissue alpha-L-fucosidase'
TargetTissue alpha-L-fucosidase(Bos taurus)
Université de Haute-Alsace

Curated by ChEMBL
LigandPNGBDBM50179482((2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidi...)
Show SMILES C[C@@H]1N[C@@H]([C@@H](O)[C@H](O)[C@@H]1O)S(O)(=O)=O
Show InChI InChI=1S/C6H13NO6S/c1-2-3(8)4(9)5(10)6(7-2)14(11,12)13/h2-10H,1H3,(H,11,12,13)/t2-,3+,4+,5-,6+/m0/s1
Affinity DataKi:  1nMAssay Description:Inhibition of bovine alpha-L-fucosidaseMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Bos taurus)
Université de Haute-Alsace

Curated by ChEMBL
LigandPNGBDBM50179481(CHEMBL203969 | L-fuco-nojirimycin)
Show SMILES C[C@@H]1NC(O)[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO4/c1-2-3(8)4(9)5(10)6(11)7-2/h2-11H,1H3/t2-,3+,4+,5-,6?/m0/s1
Affinity DataKi:  1nMAssay Description:Inhibition of bovine alpha-L-fucosidaseMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Bos taurus)
Université de Haute-Alsace

Curated by ChEMBL
LigandPNGBDBM50304627((2S,3S,4R,5R,6S)-6-methylpiperidine-2,3,4,5-tetrao...)
Show SMILES C[C@@H]1N[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO4/c1-2-3(8)4(9)5(10)6(11)7-2/h2-11H,1H3/t2-,3+,4+,5-,6-/m0/s1
Affinity DataKi:  1nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase by para-nitrophenolate release assayMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072685((3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperid...)
Show SMILES CC1C(O)C(O)C(O)C(CO)N1CC=O
Show InChI InChI=1S/C9H17NO5/c1-5-7(13)9(15)8(14)6(4-12)10(5)2-3-11/h3,5-9,12-15H,2,4H2,1H3
Affinity DataKi:  1.5nMAssay Description:Compound was tested for inhibitory activity against alpha-1,2-Fucosidase obtained from Arthrobacter oxidans F1More data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Bos taurus)
Université de Haute-Alsace

Curated by ChEMBL
LigandPNGBDBM50065258((2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2...)
Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3-,4+,5+,6-/m0/s1
Affinity DataKi:  1.70nMAssay Description:Ki value against bovine alpha-L-fucosidaseMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Bos taurus)
Université de Haute-Alsace

Curated by ChEMBL
LigandPNGBDBM50065258((2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2...)
Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3-,4+,5+,6-/m0/s1
Affinity DataKi:  3nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase by para-nitrophenolate release assayMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104394((4S,5R)-2-Methyl-piperidine-3,4,5-triol | CHEMBL87...)
Show SMILES CC1NC[C@@H](O)[C@H](O)C1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3?,4-,5?,6+/m1/s1
Affinity DataKi:  5nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Bos taurus)
Université de Haute-Alsace

Curated by ChEMBL
LigandPNGBDBM50065257((2R,3R,4R,5R,6S)-2-Hydroxymethyl-6-methyl-piperidi...)
Show SMILES C[C@@H]1N[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO4/c1-3-5(10)7(12)6(11)4(2-9)8-3/h3-12H,2H2,1H3/t3-,4+,5+,6+,7+/m0/s1
Affinity DataKi:  5.30nMAssay Description:Ki value against bovine alpha-L-fucosidaseMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Bos taurus)
Université de Haute-Alsace

Curated by ChEMBL
LigandPNGBDBM50065257((2R,3R,4R,5R,6S)-2-Hydroxymethyl-6-methyl-piperidi...)
Show SMILES C[C@@H]1N[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO4/c1-3-5(10)7(12)6(11)4(2-9)8-3/h3-12H,2H2,1H3/t3-,4+,5+,6+,7+/m0/s1
Affinity DataKi:  5.30nMAssay Description:Inhibition of bovine epididymis alpha-L-fucosidase assessed as p-nitrophenol release by spectrophotometricallyMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072588((2S,3R,4R,5R,6S)-2-Hydroxymethyl-6-methyl-piperidi...)
Show SMILES CC1NC(CO)[C@@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO4/c1-3-5(10)7(12)6(11)4(2-9)8-3/h3-12H,2H2,1H3/t3?,4?,5-,6-,7+/m1/s1
Affinity DataKi:  5.80nMAssay Description:Inhibitory activity of the compound was determined against alpha-L-fucosidase in bovine epididymis; Competitive Inhibition typeMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072588((2S,3R,4R,5R,6S)-2-Hydroxymethyl-6-methyl-piperidi...)
Show SMILES CC1NC(CO)[C@@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO4/c1-3-5(10)7(12)6(11)4(2-9)8-3/h3-12H,2H2,1H3/t3?,4?,5-,6-,7+/m1/s1
Affinity DataKi:  5.80nMAssay Description:Compound was tested for inhibitory activity (competitive) against alpha-L-fucosidase from bovine kidneyMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072588((2S,3R,4R,5R,6S)-2-Hydroxymethyl-6-methyl-piperidi...)
Show SMILES CC1NC(CO)[C@@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO4/c1-3-5(10)7(12)6(11)4(2-9)8-3/h3-12H,2H2,1H3/t3?,4?,5-,6-,7+/m1/s1
Affinity DataKi:  5.80nMAssay Description:Tested for inhibitory activity against alpha-L-fucosidase from bovine epididymus (sigma)More data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104394((4S,5R)-2-Methyl-piperidine-3,4,5-triol | CHEMBL87...)
Show SMILES CC1NC[C@@H](O)[C@H](O)C1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3?,4-,5?,6+/m1/s1
Affinity DataKi:  6nMAssay Description:Inhibitory activity against alpha-L-fucosidase of bovine epididymis expressed as KiMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065258((2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2...)
Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3-,4+,5+,6-/m0/s1
Affinity DataKi:  6.20nMAssay Description:Compound was tested for inhibitory activity (competitive) against alpha-L-fucosidase from bovine kidneyMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065258((2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2...)
Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3-,4+,5+,6-/m0/s1
Affinity DataKi:  6.20nMAssay Description:Tested for inhibitory activity against alpha-L-fucosidase from bovine epididymus (sigma)More data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065258((2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2...)
Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3-,4+,5+,6-/m0/s1
Affinity DataKi:  6.20nMAssay Description:Inhibitory activity of the compound was determined against alpha-L-fucosidase in bovine epididymis; Competitive Inhibition typeMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104387((4R,5R)-6-Hydroxymethyl-2-methyl-2,3,4,5-tetrahydr...)
Show SMILES CC1NC(CO)C(=O)[C@H](O)C1O
Show InChI InChI=1S/C7H13NO4/c1-3-5(10)7(12)6(11)4(2-9)8-3/h3-5,7-10,12H,2H2,1H3/t3?,4?,5?,7-/m1/s1
Affinity DataKi:  7nMAssay Description:Inhibitory activity against alpha-L-fucosidase of bovine epididymis expressed as KiMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072685((3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperid...)
Show SMILES CC1C(O)C(O)C(O)C(CO)N1CC=O
Show InChI InChI=1S/C9H17NO5/c1-5-7(13)9(15)8(14)6(4-12)10(5)2-3-11/h3,5-9,12-15H,2,4H2,1H3
Affinity DataKi:  8nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine kidneyMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Bos taurus)
Université de Haute-Alsace

Curated by ChEMBL
LigandPNGBDBM50304628((2S,3R,4S)-2-methyl-3,4-dihydro-2H-pyrrole-3,4-dio...)
Show SMILES C[C@@H]1NC[C@H](O)C1=O
Show InChI InChI=1S/C5H9NO2/c1-3-5(8)4(7)2-6-3/h3-4,6-7H,2H2,1H3/t3-,4-/m0/s1
Affinity DataKi:  10nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase by para-nitrophenolate release assayMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104405(3,4-Dihydroxy-5-methyl-pyrrolidine-2-sulfonic acid...)
Show SMILES CC1NC(C(O)C1O)S(O)(=O)=O
Show InChI InChI=1S/C5H11NO5S/c1-2-3(7)4(8)5(6-2)12(9,10)11/h2-8H,1H3,(H,9,10,11)
Affinity DataKi:  10nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065258((2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2...)
Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3-,4+,5+,6-/m0/s1
Affinity DataKi:  10nMAssay Description:Inhibition of human liver alpha-L-fucosidaseMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072685((3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperid...)
Show SMILES CC1C(O)C(O)C(O)C(CO)N1CC=O
Show InChI InChI=1S/C9H17NO5/c1-5-7(13)9(15)8(14)6(4-12)10(5)2-3-11/h3,5-9,12-15H,2,4H2,1H3
Affinity DataKi:  11nMAssay Description:Compound was tested for inhibitory activity against alpha-1,2-Fucosidase obtained from Arthrobacter oxidans F1More data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50403994(CHEMBL2114287)
Show SMILES C[C@@H]1C[C@@H](N)[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO3/c1-3-2-4(8)6(10)7(11)5(3)9/h3-7,9-11H,2,8H2,1H3/t3-,4-,5-,6-,7-/m1/s1
Affinity DataKi:  12nMAssay Description:The compound was tested for the inhibitory activity against alpha-L-Fucosidase in bovine kidneyMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50403995(CHEMBL2115269)
Show SMILES C[C@@H]1C[C@H](N)[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO3/c1-3-2-4(8)6(10)7(11)5(3)9/h3-7,9-11H,2,8H2,1H3/t3-,4+,5-,6-,7-/m1/s1
Affinity DataKi:  12nMAssay Description:The compound was tested for the inhibitory activity against alpha-L-Fucosidase in bovine kidneyMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50118923((1S,2S,3R)-4-Methyl-6-octylamino-cyclohexane-1,2,3...)
Show SMILES CCCCCCCCNC1CC(C)C(O)C(O)C1O
Show InChI InChI=1S/C15H31NO3/c1-3-4-5-6-7-8-9-16-12-10-11(2)13(17)15(19)14(12)18/h11-19H,3-10H2,1-2H3
Affinity DataKi:  16nMAssay Description:Binding affinity against alpha-L-fucosidase in bovine kidney was determinedMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104403((2R,3S)-2-Amino-5-methyl-piperidine-3,4-diol | CHE...)
Show SMILES CC1CN[C@@H](N)[C@H](O)C1O
Show InChI InChI=1S/C6H14N2O2/c1-3-2-8-6(7)5(10)4(3)9/h3-6,8-10H,2,7H2,1H3/t3?,4?,5-,6-/m1/s1
Affinity DataKi:  16nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072687((S)-2-Amino-3-hydroxy-N-(3,4,5-trihydroxy-2-hydrox...)
Show SMILES CC1NC(CO)(CNC(=O)[C@@H](N)CO)C(O)C(O)C1O
Show InChI InChI=1S/C11H23N3O6/c1-5-7(17)8(18)9(19)11(4-16,14-5)3-13-10(20)6(12)2-15/h5-9,14-19H,2-4,12H2,1H3,(H,13,20)/t5?,6-,7?,8?,9?,11?/m0/s1
Affinity DataKi:  19nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine epididymisMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065258((2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2...)
Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3-,4+,5+,6-/m0/s1
Affinity DataKi:  29nMAssay Description:Inhibition constant against Alpha-FucosidaseMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072687((S)-2-Amino-3-hydroxy-N-(3,4,5-trihydroxy-2-hydrox...)
Show SMILES CC1NC(CO)(CNC(=O)[C@@H](N)CO)C(O)C(O)C1O
Show InChI InChI=1S/C11H23N3O6/c1-5-7(17)8(18)9(19)11(4-16,14-5)3-13-10(20)6(12)2-15/h5-9,14-19H,2-4,12H2,1H3,(H,13,20)/t5?,6-,7?,8?,9?,11?/m0/s1
Affinity DataKi:  30nMAssay Description:Compound was tested for inhibitory activity against alpha-1,2-Fucosidase obtained from Arthrobacter oxidans F1More data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065258((2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2...)
Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3-,4+,5+,6-/m0/s1
Affinity DataKi:  31nMAssay Description:Binding affinity against alpha-L-fucosidase in bovine kidney was determinedMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50118928((1S,2S,3R)-4-Methyl-6-phenethylamino-cyclohexane-1...)
Show SMILES CC1CC(NCCc2ccccc2)C(O)C(O)C1O
Show InChI InChI=1S/C15H23NO3/c1-10-9-12(14(18)15(19)13(10)17)16-8-7-11-5-3-2-4-6-11/h2-6,10,12-19H,7-9H2,1H3
Affinity DataKi:  32nMAssay Description:Binding affinity against alpha-L-fucosidase in bovine kidney was determinedMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072687((S)-2-Amino-3-hydroxy-N-(3,4,5-trihydroxy-2-hydrox...)
Show SMILES CC1NC(CO)(CNC(=O)[C@@H](N)CO)C(O)C(O)C1O
Show InChI InChI=1S/C11H23N3O6/c1-5-7(17)8(18)9(19)11(4-16,14-5)3-13-10(20)6(12)2-15/h5-9,14-19H,2-4,12H2,1H3,(H,13,20)/t5?,6-,7?,8?,9?,11?/m0/s1
Affinity DataKi:  47nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine kidneyMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50118921((1R,2S,3S)-4-Heptylamino-6-methyl-cyclohexane-1,2,...)
Show SMILES CCCCCCCNC1CC(C)C(O)C(O)C1O
Show InChI InChI=1S/C14H29NO3/c1-3-4-5-6-7-8-15-11-9-10(2)12(16)14(18)13(11)17/h10-18H,3-9H2,1-2H3
Affinity DataKi:  48nMAssay Description:Binding affinity against alpha-L-fucosidase in bovine kidney was determinedMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Bos taurus)
Université de Haute-Alsace

Curated by ChEMBL
LigandPNGBDBM50242272(6-O-alpha-rhamnopyranosyl-DMJ | CHEMBL469655)
Show SMILES C[C@H]1O[C@H](OC[C@H]2NC[C@@H](O)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C12H23NO8/c1-4-7(15)10(18)11(19)12(21-4)20-3-5-8(16)9(17)6(14)2-13-5/h4-19H,2-3H2,1H3/t4-,5-,6-,7-,8-,9-,10+,11+,12+/m1/s1
Affinity DataKi:  60nMAssay Description:Inhibition of bovine epididymis alpha-L-fucosidase assessed as p-nitrophenol release by spectrophotometricallyMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50118920((1R,2S,3S)-4-Benzylamino-6-methyl-cyclohexane-1,2,...)
Show SMILES CC1CC(NCc2ccccc2)C(O)C(O)C1O
Show InChI InChI=1S/C14H21NO3/c1-9-7-11(13(17)14(18)12(9)16)15-8-10-5-3-2-4-6-10/h2-6,9,11-18H,7-8H2,1H3
Affinity DataKi:  69nMAssay Description:Binding affinity against alpha-L-fucosidase in bovine kidney was determinedMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50118922((1R,2S,3S)-4-Butylamino-6-methyl-cyclohexane-1,2,3...)
Show SMILES CCCCNC1CC(C)C(O)C(O)C1O
Show InChI InChI=1S/C11H23NO3/c1-3-4-5-12-8-6-7(2)9(13)11(15)10(8)14/h7-15H,3-6H2,1-2H3
Affinity DataKi:  74nMAssay Description:Binding affinity against alpha-L-fucosidase in bovine kidney was determinedMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Bos taurus)
Université de Haute-Alsace

Curated by ChEMBL
LigandPNGBDBM50163439((2S,3R,4S,5R)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Show SMILES OC[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5+,6-/m0/s1
Affinity DataKi:  80nMAssay Description:Ki value against bovine alpha-L-fucosidaseMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065258((2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2...)
Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3-,4+,5+,6-/m0/s1
Affinity DataKi:  80nMAssay Description:Inhibitory activity measured against alpha-L-fucosidase of bovine epididymis by colorimetric assay using the D-glucose oxidase-peroxidase methodMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065257((2R,3R,4R,5R,6S)-2-Hydroxymethyl-6-methyl-piperidi...)
Show SMILES C[C@@H]1N[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO4/c1-3-5(10)7(12)6(11)4(2-9)8-3/h3-12H,2H2,1H3/t3-,4+,5+,6+,7+/m0/s1
Affinity DataKi:  80nMAssay Description:Inhibitory activity measured against alpha-L-fucosidase of bovine epididymis by colorimetric assay using the D-glucose oxidase-peroxidase methodMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50118919((1S,2S,3R)-4-Methyl-6-nonylamino-cyclohexane-1,2,3...)
Show SMILES CCCCCCCCCNC1CC(C)C(O)C(O)C1O
Show InChI InChI=1S/C16H33NO3/c1-3-4-5-6-7-8-9-10-17-13-11-12(2)14(18)16(20)15(13)19/h12-20H,3-11H2,1-2H3
Affinity DataKi:  110nMAssay Description:Binding affinity against alpha-L-fucosidase in bovine kidney was determinedMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104402(2-Methyl-3,4-dihydro-2H-pyrrole-3,4-diol | CHEMBL8...)
Show SMILES CC1NCC(O)C1=O
Show InChI InChI=1S/C5H9NO2/c1-3-5(8)4(7)2-6-3/h3-4,6-7H,2H2,1H3
Affinity DataKi:  160nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50118926((1R,2S,3S)-4-Ethylamino-6-methyl-cyclohexane-1,2,3...)
Show SMILES CCNC1CC(C)C(O)C(O)C1O
Show InChI InChI=1S/C9H19NO3/c1-3-10-6-4-5(2)7(11)9(13)8(6)12/h5-13H,3-4H2,1-2H3
Affinity DataKi:  180nMAssay Description:Binding affinity against alpha-L-fucosidase in bovine kidney was determinedMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50403995(CHEMBL2115269)
Show SMILES C[C@@H]1C[C@H](N)[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO3/c1-3-2-4(8)6(10)7(11)5(3)9/h3-7,9-11H,2,8H2,1H3/t3-,4+,5-,6-,7-/m1/s1
Affinity DataKi:  200nMAssay Description:The compound was tested for the inhibitory activity against alpha-L-Fucosidase in bovine kidneyMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104390((R)-2-((R)-2-Allyloxy-4,5-dihydroxy-6-hydroxymethy...)
Show SMILES CC1SC(O[C@H]2C(OCC=C)OC(CO)C(O)C2O)C(O)[C@H](O)C1O
Show InChI InChI=1S/C15H26O9S/c1-3-4-22-14-13(11(20)9(18)7(5-16)23-14)24-15-12(21)10(19)8(17)6(2)25-15/h3,6-21H,1,4-5H2,2H3/t6?,7?,8?,9?,10-,11?,12?,13-,14?,15?/m1/s1
Affinity DataKi:  210nMAssay Description:Inhibitory activity against alpha-L-fucosidase of bacillus species (K40T) expressed as KiMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104410((2R,3R)-4-Amino-6-methyl-cyclohexane-1,2,3-triol |...)
Show SMILES CC1CC(N)[C@@H](O)[C@H](O)C1O
Show InChI InChI=1S/C7H15NO3/c1-3-2-4(8)6(10)7(11)5(3)9/h3-7,9-11H,2,8H2,1H3/t3?,4?,5?,6-,7-/m1/s1
Affinity DataKi:  230nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Bos taurus)
Université de Haute-Alsace

Curated by ChEMBL
LigandPNGBDBM50369362(CHEMBL1169500)
Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)C(O)[C@H]1O
Show InChI InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3-,4-,5+,6+/m1/s1
Affinity DataKi:  450nMAssay Description:Ki value against bovine alpha-L-fucosidaseMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Bos taurus)
Université de Haute-Alsace

Curated by ChEMBL
LigandPNGBDBM50242268(2,5-Imino-1,2,5-trideoxy-L-glucitol | CHEMBL502230)
Show SMILES C[C@H]1N[C@@H](CO)[C@H](O)[C@H]1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(2-8)7-3/h3-10H,2H2,1H3/t3-,4+,5+,6+/m1/s1
Affinity DataKi:  490nMAssay Description:Inhibition of bovine epididymis alpha-L-fucosidase assessed as p-nitrophenol release by spectrophotometricallyMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50182797(5-(dimethylamino)-N-(6-((2S,3R,4S,5R)-3,4,5-trihyd...)
Show SMILES C[C@H]1[C@@H](O)[C@@H](O)[C@H](O)CN1CCCCCCNS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C24H37N3O5S/c1-17-23(29)24(30)21(28)16-27(17)15-7-5-4-6-14-25-33(31,32)22-13-9-10-18-19(22)11-8-12-20(18)26(2)3/h8-13,17,21,23-25,28-30H,4-7,14-16H2,1-3H3/t17-,21+,23+,24-/m0/s1
Affinity DataKi:  500nMAssay Description:Inhibition of human liver alpha-L-fucosidaseMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104399((R)-4-Benzylamino-5-methyl-cyclopentane-1,2,3-trio...)
Show SMILES CC1C(O)[C@@H](O)C(O)C1NCc1ccccc1
Show InChI InChI=1S/C13H19NO3/c1-8-10(12(16)13(17)11(8)15)14-7-9-5-3-2-4-6-9/h2-6,8,10-17H,7H2,1H3/t8?,10?,11?,12?,13-/m1/s1
Affinity DataKi:  680nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104395((4R,5R)-6-Hydrazino-2-methyl-2,3,4,5-tetrahydro-py...)
Show SMILES CC1N=C(NN)[C@@H](O)[C@H](O)C1O
Show InChI InChI=1S/C6H13N3O3/c1-2-3(10)4(11)5(12)6(8-2)9-7/h2-5,10-12H,7H2,1H3,(H,8,9)/t2?,3?,4-,5+/m1/s1
Affinity DataKi:  820nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
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