Compile Data Set for Download or QSAR
Report error Found 15321 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3'
TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100348(US8501944, 374 | US8501944, 370 | US9868729, Examp...)
Affinity DataKd:  2.90nMAssay Description:ATP-site dependent competition binding assay using Ambit KinomeScan Screening kit.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100349(US8501944, 371 | US9868729, Example 207 | US105330...)
Affinity DataKd:  3nMAssay Description:ATP-site dependent competition binding assay using Ambit KinomeScan Screening kit.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100350(US8501944, 375 | US8501944, 372 | US9868729, Examp...)
Affinity DataKd:  2.70nMAssay Description:ATP-site dependent competition binding assay using Ambit KinomeScan Screening kit.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100351(US8501944, 376 | US8501944, 373 | US9868729, Examp...)
Affinity DataKd:  4.10nMAssay Description:ATP-site dependent competition binding assay using Ambit KinomeScan Screening kit.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100348(US8501944, 374 | US8501944, 370 | US9868729, Examp...)
Affinity DataKd:  2.90nMAssay Description:ATP-site dependent competition binding assay using Ambit KinomeScan Screening kit.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100351(US8501944, 376 | US8501944, 373 | US9868729, Examp...)
Affinity DataKd:  4.10nMAssay Description:ATP-site dependent competition binding assay using Ambit KinomeScan Screening kit.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100348(US8501944, 374 | US8501944, 370 | US9868729, Examp...)
Affinity DataKd:  2.90nMAssay Description:This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2015
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100349(US8501944, 371 | US9868729, Example 207 | US105330...)
Affinity DataKd:  3nMAssay Description:This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2015
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100350(US8501944, 375 | US8501944, 372 | US9868729, Examp...)
Affinity DataKd:  2.70nMAssay Description:This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2015
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100351(US8501944, 376 | US8501944, 373 | US9868729, Examp...)
Affinity DataKd:  4.10nMAssay Description:This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2015
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100348(US8501944, 374 | US8501944, 370 | US9868729, Examp...)
Affinity DataKd:  2.90nMAssay Description:This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2015
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100350(US8501944, 375 | US8501944, 372 | US9868729, Examp...)
Affinity DataKd:  2.70nMAssay Description:This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2015
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100351(US8501944, 376 | US8501944, 373 | US9868729, Examp...)
Affinity DataKd:  4.10nMAssay Description:This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2015
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM214688(US9295672, (4-fluorophenyl)(4-((5-methyl-1H-pyraz...)
Affinity DataKd:  1.05E+4nMT: 2°CAssay Description:For the binding assays, streptavidin-coated magnetic beads were treated with biotinylated affinity ligands for 30 min at room temperature to generate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2017
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM214689(US9295672, (S)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataKd:  5.00E+3nMT: 2°CAssay Description:For the binding assays, streptavidin-coated magnetic beads were treated with biotinylated affinity ligands for 30 min at room temperature to generate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2017
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM214690(US9295672, (R)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataKd:  2.10E+4nMT: 2°CAssay Description:For the binding assays, streptavidin-coated magnetic beads were treated with biotinylated affinity ligands for 30 min at room temperature to generate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2017
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM202553((E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidaz...)
Affinity DataKd:  1.34nMAssay Description:The assay is based on the displacement of a reporter probe by a test compound. Close proximity of the probe and the targeted kinase result in emissio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM374713(US10246466, Example 20 | 11-fluoro-14-methyl-6,7,1...)
Affinity DataKd:  120nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., A small molecule-kinase interaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM374716(US10246466, Example 41 | 10-fluoro-8-methyl-15,16-...)
Affinity DataKd:  33nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., A small molecule-kinase interaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM374722(US10246466, Example 51 | 11-fluoro-13-methyl-6,7,1...)
Affinity DataKd:  4.30nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., A small molecule-kinase interaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM374723(US10246466, Example 51-1 | (13R)-11-fluoro-13-meth...)
Affinity DataKd:  1.80nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., A small molecule-kinase interaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataKd:  200nMAssay Description:Binding constant for JAK3(JH1domain-catalytic) kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataKd:  420nMAssay Description:Binding constant for JAK3(Kin.Dom.2/JH1 - catalytic) kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100348(US8501944, 374 | US8501944, 370 | US9868729, Examp...)
Affinity DataKd:  2.90nMAssay Description:Syk and JAK: The activity of a specified compound as an inhibitor of a JAK kinase may be assessed in vitro or in vivo. In some embodiments, the activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM475681((4aS,8aR)-8a-methyl-7-(7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataEC50:  924nMAssay Description:Inhibition of phosphorylation of a synthetic peptide was measured in an HTRF-based assay using the TK substrate-Biotin from the Cisbio HTRFKinEASE TK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM374722(US10246466, Example 51 | 11-fluoro-13-methyl-6,7,1...)
Affinity DataKd:  4.30nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., A small molecule-kinase interaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM475707((3aS,7aS)-3a-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataEC50:  118nMAssay Description:Inhibition of phosphorylation of a synthetic peptide was measured in an HTRF-based assay using the TK substrate-Biotin from the Cisbio HTRFKinEASE TK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataKd:  1.20E+3nMAssay Description:Binding constant for JAK3(JH1domain-catalytic) kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM21079(1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for JAK3(JH1domain-catalytic) kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM5931(cid_3025986 | CHEMBL296468 | N-(5-{[(5-tert-butyl-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for JAK3(Kin.Dom.2/JH1 - catalytic) kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM475703(2-[(4aR*,8aS*)-8a-ethyl-7-(7H-pyrrolo[2,3-d]pyrimi...)
Affinity DataEC50:  29nMAssay Description:Inhibition of phosphorylation of a synthetic peptide was measured in an HTRF-based assay using the TK substrate-Biotin from the Cisbio HTRFKinEASE TK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM50605511(CHEMBL5193786)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to wild type human partial length JAK3 (I781 to S1124 residues) expressed in mammalian expression system by Kinomescan binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM475687((4aR*,8aS*)-8a-methyl-7-(7H-pyrrolo[2,3-d]pyrimidi...)
Affinity DataEC50:  8nMAssay Description:Inhibition of phosphorylation of a synthetic peptide was measured in an HTRF-based assay using the TK substrate-Biotin from the Cisbio HTRFKinEASE TK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM466434((8S)-N-[(1S)-1-(4- cyano-2-methoxy- phenyl)ethyl]-...)
Affinity DataEC50:  226nMAssay Description:Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM466457((8S)-N-[(1R)-1-(4- cyano-2-methoxy- phenyl)-2- hyd...)
Affinity DataEC50:  154nMAssay Description:Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM466460(N-[(1R)-1-(3- cyano-4-fluoro- phenyl)ethyl]-5- (7H...)
Affinity DataEC50:  63.9nMAssay Description:Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  260nMAssay Description:Binding constant for JAK3(Kin.Dom.2/JH1 - catalytic) kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataKd:  2.20nMAssay Description:Binding constant for JAK3(Kin.Dom.2/JH1 - catalytic) kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM466410(N-[(3- cyanophenyl) methyl]-5-(7H- pyrrolo[2,3- d]...)
Affinity DataEC50:  32.6nMAssay Description:Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  2.30nMAssay Description:Binding constant for JAK3(JH1domain-catalytic) kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM4779(cid_156414 | PD0183805 | CHEMBL545315 | CHEMBL3196...)
Affinity DataKd:  630nMAssay Description:Binding constant for JAK3(JH1domain-catalytic) kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM13535(N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidin...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for JAK3(Kin.Dom.2/JH1 - catalytic) kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM466448(N-[(1R)-1-(4- cyanophenyl)ethyl]- 5-(7H- pyrrolo[2...)
Affinity DataEC50:  123nMAssay Description:Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for JAK3(JH1domain-catalytic) kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM475694((4aR*,8aS*)-8a-ethyl-7-(7H-pyrrolo[2,3-d]pyrimidin...)
Affinity DataEC50:  43nMAssay Description:Inhibition of phosphorylation of a synthetic peptide was measured in an HTRF-based assay using the TK substrate-Biotin from the Cisbio HTRFKinEASE TK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM466352((8S)-N-[(2R)-2- hydroxy-2- tetrahydropyran- 4-yl-e...)
Affinity DataEC50:  11.7nMAssay Description:Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM466371((8S)-N-[(2R)-2-(4- cyanophenyl)-2- hydroxy-ethyl]-...)
Affinity DataEC50:  6.5nMAssay Description:Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM466429(cyclopropylmethyl (2R)-3-hydroxy- 2-[[(8S)-5-(7H- ...)
Affinity DataEC50:  47.3nMAssay Description:Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  260nMAssay Description:Binding constant for JAK3(JH1domain-catalytic) kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM50382959(CEP-32496 | CHEMBL2029988 | US9730937, Example 261)
Affinity DataKd: >1.00E+4nMAssay Description:Inhibition of JAK3 in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Displayed 1 to 50 (of 15321 total ) | Next | Last >>
Jump to: