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Report error Found 4571 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kin...
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299749(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0100nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299902(6-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0120nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299975(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0120nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300011(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi: <0.0130nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300079(N-[(2R)-1- hydroxypropan-2- yl]-6-[4-(4- methoxy-1...)
Affinity DataKi: <0.0130nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300077(N-(3-amino-3- methylbutan- 2-yl)-2- (cyclo- propyl...)
Affinity DataKi: <0.0130nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300035(2-(benzyloxy)-N- [(2R)-1- hydroxypropan-2- yl]-6-[...)
Affinity DataKi: <0.0130nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300088(N-[(2R)-1- hydroxypropan-2- yl]-2-[(2R)-2- methoxy...)
Affinity DataKi:  0.0140nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299998(N-[(2R)-1- hydroxypropan-2- yl]-6-[4-(4- methoxy-1...)
Affinity DataKi:  0.0150nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299931(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0150nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299744(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0160nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299909(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0160nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300012(N-(2- methoxyethyl)-6- [4-(4-methoxy-1H- pyrrolo[2...)
Affinity DataKi:  0.0160nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300049((3,3- difluoroazetidin-1- yl)(2-{[(2R)-1- methoxyp...)
Affinity DataKi:  0.0180nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300007(2-[(1- cyanocyclopropyl) methoxy]-N-[(2R)- 1-hydro...)
Affinity DataKi: <0.0180nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299893(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0190nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300090(N-[(2R)-1- hydroxypropan-2- yl]-2-[(2S)-2- methoxy...)
Affinity DataKi:  0.0200nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299917(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0200nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300070(N-[(2R)-3- hydroxy-3- methylbutan-2-yl]- 4-[4-(4-m...)
Affinity DataKi:  0.0200nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299996(4-[(1- cyanocyclopropyl) methoxy]-6-[4-(4- methoxy...)
Affinity DataKi:  0.0210nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300125(N-cyclobutyl-4- {[(2R)-1- methoxypropan-2- yl]oxy}...)
Affinity DataKi:  0.0210nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299901(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0210nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300104(4-(benzyloxy)-N- [(2R)-1- hydroxypropan-2- yl]-6-[...)
Affinity DataKi:  0.0250nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299891(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0260nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300064(N-[(2R)-1- hydroxypropan-2- yl]-4-{[(2R)-1- methox...)
Affinity DataKi:  0.0280nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299746(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0280nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299890(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0280nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299930(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0290nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300103(4-[(1- cyanocyclopropyl) methoxy]-N-[(2R)- 1-hydro...)
Affinity DataKi:  0.0300nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299803(N- (bicyclo[1.1.1]pent- 1-yl)-4-{[(1S,2R)- 2- cyan...)
Affinity DataKi:  0.0300nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300071(N-[(2R)-1- hydroxypropan-2- yl]-4-[4-(4- methoxy-1...)
Affinity DataKi:  0.0300nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299852(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0320nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300099(4-{[(1S,2R)-2- cyanocyclopropyl] methoxy}-N-[(2R)-...)
Affinity DataKi:  0.0320nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299922(6-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0330nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300056(N-(3-amino-3- methylbutan-2-yl)- 2-{[(2R)-1- metho...)
Affinity DataKi:  0.0340nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299911(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0340nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300087(N-[(1R,2R)-2- hydroxy- cyclobutyl]- 6-[4-(4-methox...)
Affinity DataKi:  0.0340nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300098(4-{[(1S,2R)-2- cyanocyclopropyl] methoxy}-N-[(2R)-...)
Affinity DataKi:  0.0350nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300101(4-(benzyloxy)-N- [(2R)-1- hydroxypropan-2- yl]-6-[...)
Affinity DataKi:  0.0370nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300102(4-[(1- cyanocyclopropyl) methoxy]-N-[(2R)- 3-hydro...)
Affinity DataKi:  0.0380nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300063(N-[(2R)-3- hydroxy-3- methylbutan-2-yl]- 4-{[(2R)-...)
Affinity DataKi:  0.0380nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299849(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0390nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299876(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0400nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300061(N-(3-amino-3- methylbutan-2-yl)- 2-[(1- cyanocyclo...)
Affinity DataKi:  0.0400nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300065((trans)-N-(2- hydroxy- cyclobutyl)- 2-{[(2R)-1- me...)
Affinity DataKi:  0.0410nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300107(N-[(1R,2S)-2- hydroxycyclobutyl]- 6-[4-(4-methoxy-...)
Affinity DataKi:  0.0420nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299851(4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...)
Affinity DataKi:  0.0420nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299995(4-[(1- cyanocyclopropyl) methoxy]-6-[4-(4- methoxy...)
Affinity DataKi:  0.0480nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300091(N-[(3R,4S)-4- hydroxytetrahydro- furan-3-yl]-2- {[...)
Affinity DataKi:  0.0480nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300053(2-[(1- cyanocyclopropyl) methoxy]-N-[(2R)- 1-hydro...)
Affinity DataKi:  0.0490nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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