Compile Data Set for Download or QSAR
Report error Found 120 Enz. Inhib. hit(s) with all data for entry = 11680
TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639195BDBM639195((S)-7-isopropoxy-1-((5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 1.70nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639244BDBM639244(1-(((S)-4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 2nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639196BDBM639196((S)-7-isopropoxy-4-((1-methylpiperidin-4-yl)ethyny...)
Affinity DataIC50: 2.30nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639254BDBM639254((S)-1-((4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 2.40nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639204BDBM639204((S)-7-isopropoxy-4-((1-methylazetidin-3-yl)ethynyl...)
Affinity DataIC50: 2.60nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639241BDBM639241((S)-4-(azetidin-3-ylethynyl)-1-((4,4-difluoro-5-ox...)
Affinity DataIC50: 2.80nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639251BDBM639251(1-(((S)-4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 3nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639281BDBM639281(1-(((R)-1-(2-cyanoacetyl)piperidin-3-yl)oxy)-4-((c...)
Affinity DataIC50: 3.20nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639203BDBM639203((S)-4-(azetidin-3-ylethynyl)-7-isopropoxy-1-((5-ox...)
Affinity DataIC50: 3.30nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639234BDBM639234((S)-1-((4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 3.30nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639209BDBM639209(4-((cis-3-(dimethylamino)cyclobutyl)ethynyl)-7-iso...)
Affinity DataIC50: 3.5nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639233BDBM639233((S)-1-((4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 3.5nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639256BDBM639256(1-(((S)-4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 3.60nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639242BDBM639242((S)-1-((4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 3.60nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639237BDBM639237(1-(((S)-4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 3.90nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639253BDBM639253((S)-1-((4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 4nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639180BDBM639180((S)-4-bromo-1-((4,4-difluoro-5-oxopyrrolidin-2-yl)...)
Affinity DataIC50: 4.40nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639226BDBM639226((S)-1-((4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 4.40nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639235BDBM639235((S)-1-((4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 4.5nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639228BDBM639228((S)-1-((4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 4.80nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639221BDBM639221(4-(1-(cis-3-(dimethylamino)cyclobutyl)-1H-pyrazol-...)
Affinity DataIC50: 5nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639247BDBM639247((S)-4-(1-cyclopentyl-1H-pyrazol-4-yl)-1-((4,4-difl...)
Affinity DataIC50: 5.10nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639184BDBM639184((S)-7-isopropoxy-1-((5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 5.10nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639278BDBM639278((R)-4-(azetidin-3-ylethynyl)-1-((1-(2-cyanoacetyl)...)
Affinity DataIC50: 5.20nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639229BDBM639229((S)-1-((4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 5.30nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639182BDBM639182((S)-4-((3-hydroxyoxetan-3-yl)ethynyl)-7-isopropoxy...)
Affinity DataIC50: 5.30nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639192BDBM639192((S)-4-((4-hydroxy-1-methylpiperidin-4-yl)ethynyl)-...)
Affinity DataIC50: 5.40nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639207BDBM639207((S)-7-isopropoxy-4-((1-(methylcarbamoyl)azetidin-3...)
Affinity DataIC50: 5.5nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639205BDBM639205((S)-7-isopropoxy-4-((1-isopropylazetidin-3-yl)ethy...)
Affinity DataIC50: 5.60nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639199BDBM639199(4-((cis-4-ethoxycyclohexyl)ethynyl)-7-isopropoxy-1...)
Affinity DataIC50: 5.60nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639245BDBM639245((S)-4-(1-cyclopropyl-1H-pyrazol-4-yl)-1-((4,4-difl...)
Affinity DataIC50: 6.30nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639206BDBM639206(methyl (S)-3-((6-carbamoyl-7-isopropoxy-1-((5-oxop...)
Affinity DataIC50: 6.30nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639231BDBM639231((S)-1-((4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 6.30nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639208BDBM639208((S)-4-((3,3-dimethoxycyclobutyl)ethynyl)-7-isoprop...)
Affinity DataIC50: 6.40nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639220BDBM639220(4-(1-(cis-3-ethoxycyclobutyl)-1H-pyrazol-4-yl)-7-i...)
Affinity DataIC50: 6.40nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639249BDBM639249((S)-1-((4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 6.40nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639197BDBM639197((S)-7-isopropoxy-4-((1-isopropylpiperidin-4-yl)eth...)
Affinity DataIC50: 6.70nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639248BDBM639248((S)-1-((4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 6.80nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639298BDBM639298(1-(((R)-1-(2-cyanoacetyl)piperidin-3-yl)oxy)-4-(1-...)
Affinity DataIC50: 6.80nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639198BDBM639198(4-(((1r,4S)-4-ethoxycyclohexyl)ethynyl)-7-isopropo...)
Affinity DataIC50: 7nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639255BDBM639255(1-(((S)-4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 7nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639250BDBM639250((S)-1-((4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 7nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639279BDBM639279((R)-1-((1-(2-cyanoacetyl)piperidin-3-yl)oxy)-7-iso...)
Affinity DataIC50: 7.10nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639211BDBM639211((S)-4-(1-cyclobutyl-1H-pyrazol-4-yl)-7-isopropoxy-...)
Affinity DataIC50: 7.5nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639227BDBM639227((S)-1-((4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)...)
Affinity DataIC50: 7.60nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639225BDBM639225(rrr | US20230391748, Compound I-47)
Affinity DataIC50: 7.60nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639212BDBM639212((S)-4-(1-cyclopentyl-1H-pyrazol-4-yl)-7-isopropoxy...)
Affinity DataIC50: 7.70nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639290BDBM639290((R)-1-((1-(2-cyanoacetyl)piperidin-3-yl)oxy)-4-(1-...)
Affinity DataIC50: 7.70nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639271BDBM639271((R)-1-((1-(2-cyanoacetyl)piperidin-3-yl)oxy)-7-iso...)
Affinity DataIC50: 8nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 639202BDBM639202(tert-butyl (S)-3-((6-carbamoyl-7-isopropoxy-1-((5-...)
Affinity DataIC50: 8.10nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

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