Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50041293
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50143314BDBM50143314(CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...)
Affinity DataKi:  0.0180nMAssay Description:Inhibition of [3H]epibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100717BDBM50100717(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | CHE...)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of [3H]epibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100715BDBM50100715(2-(6-Bromo-pyridin-3-yl)-7-aza-bicyclo[2.2.1]hepta...)
Affinity DataKi:  0.0230nMAssay Description:Inhibition of [3H]epibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50143320BDBM50143320(2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]hept...)
Affinity DataKi:  0.0260nMAssay Description:Inhibition of [3H]epibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100707BDBM50100707((R)-2-(6-Fluoro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]...)
Affinity DataKi:  0.0270nMAssay Description:Inhibition of [3H]epibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100717BDBM50100717(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | CHE...)
Affinity DataKi:  0.0310nMAssay Description:Non-specific binding in presence of 300 uM nicotine at nicotinic acetylcholine receptor alpha4-beta2 in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50143320BDBM50143320(2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]hept...)
Affinity DataKi:  0.0450nMAssay Description:Non-specific binding in presence of 300 uM nicotine at nicotinic acetylcholine receptor alpha4-beta2 in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50143314BDBM50143314(CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...)
Affinity DataKi:  0.0580nMAssay Description:Non-specific binding in presence of 300 uM nicotine at nicotinic acetylcholine receptor alpha4-beta2 in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100712BDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of [3H]epibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100706BDBM50100706(2-Bromo-5-(1-methyl-pyrrolidin-2-yl)-pyridine | CH...)
Affinity DataKi:  0.450nMAssay Description:Inhibition of [3H]-nicotine binding at the nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100712BDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)
Affinity DataKi:  0.480nMAssay Description:Non-specific binding in presence of 300 uM nicotine at nicotinic acetylcholine receptor alpha4-beta2 in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50078056BDBM50078056(2-Chloro-5-(1-methyl-pyrrolidin-2-yl)-pyridine | C...)
Affinity DataKi:  0.630nMAssay Description:Inhibition of [3H]-nicotine binding at the nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82070BDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  1.01nMAssay Description:Non-specific binding in presence of 300 uM nicotine at nicotinic acetylcholine receptor alpha4-beta2 in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100709BDBM50100709(2-Fluoro-5-(1-methyl-pyrrolidin-2-yl)-pyridine | C...)
Affinity DataKi:  1.03nMAssay Description:Inhibition of [3H]-nicotine binding at the nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004108BDBM50004108((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...)
Affinity DataKi:  1.26nMAssay Description:Inhibition of [3H]-nicotine binding at the nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100713BDBM50100713(5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-ylamin...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of [3H]epibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82070BDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of [3H]epibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100708BDBM50100708(5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridine-2-sulfo...)
Affinity DataKi:  8.5nMAssay Description:Inhibition of [3H]epibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100711BDBM50100711([5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-yl]-d...)
Affinity DataKi:  26.4nMAssay Description:Inhibition of [3H]epibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100716BDBM50100716(5-(1-Methyl-pyrrolidin-2-yl)-pyridin-2-ylamine | C...)
Affinity DataKi:  81nMAssay Description:Inhibition of [3H]-nicotine binding at the nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100714BDBM50100714(5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-ol | C...)
Affinity DataKi:  107nMAssay Description:Inhibition of [3H]pibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100710BDBM50100710(5-(1-methylpyrrolidin-2-yl)pyridin-2-ol | 6-hydrox...)
Affinity DataKi:  1.07E+3nMAssay Description:Inhibition of [3H]-nicotine binding at the nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed