BindingDB PrimarySearch

Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50011684

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109298(CHEMBL344162 | [5-({[4-(1H-Benzoimidazol-2-ylamino...)

IC50: 1.60nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109296((5-{[4-(1H-Benzoimidazol-2-ylamino)-benzylcarbamoy...)

IC50: 7nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109296((5-{[4-(1H-Benzoimidazol-2-ylamino)-benzylcarbamoy...)

IC50: 7.30nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109305((5-{[5-(1H-Benzoimidazol-2-ylamino)-pentylcarbamoy...)

IC50: 13nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109307((5-{[4-(1H-Benzoimidazol-2-ylamino)-butylcarbamoyl...)

IC50: 15nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109303((5-{[4-(3-Benzyl-ureido)-benzylcarbamoyl]-methyl}-...)

IC50: 23nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109298(CHEMBL344162 | [5-({[4-(1H-Benzoimidazol-2-ylamino...)

IC50: 40nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109293((5-{[4-(1H-Benzoimidazol-2-yl)-benzylcarbamoyl]-me...)

IC50: 74nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109301(CHEMBL139506 | {5-[(4-Guanidino-benzylcarbamoyl)-m...)

IC50: 84nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109300(CHEMBL336870 | [5-({[4-(1H-Benzoimidazol-2-yl)-thi...)

IC50: 100nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109296((5-{[4-(1H-Benzoimidazol-2-ylamino)-benzylcarbamoy...)

IC50: 100nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109299(CHEMBL342191 | [5-({[6-(1H-Benzoimidazol-2-yl)-pyr...)

IC50: 200nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109312((5-{[4-(5,6-Dimethyl-1H-benzoimidazol-2-yl)-benzyl...)

IC50: 220nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109289(CHEMBL136783 | [6-Oxo-5-({[4-(pyridin-2-ylaminomet...)

IC50: 220nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109310(CHEMBL138724 | [5-({2-[4-(1H-Benzoimidazol-2-yl)-p...)

IC50: 380nMAssay Description:Displacement of alphaIIb-beta3 integrin from fibrinogen by ELISAMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109304(CHEMBL138888 | [5-({[4-(3H-Imidazo[4,5-b]pyridin-2...)

IC50: 500nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109290(CHEMBL423537 | [5-({[5-(1H-Benzoimidazol-2-yl)-thi...)

IC50: 500nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109302((5-{[4-(5-Chloro-1H-benzoimidazol-2-yl)-benzylcarb...)

IC50: 620nMAssay Description:Displacement of alphaIIb-beta3 integrin from fibrinogen by ELISAMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109309((6-Oxo-5-{[3-(pyridin-2-ylamino)-propylcarbamoyl]-...)

IC50: 1.00E+3nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109297((5-{[(1H-Benzoimidazol-2-ylmethyl)-carbamoyl]-meth...)

IC50: 1.00E+3nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109291((5-{[(4-Carbamimidoyl-thiophen-2-ylmethyl)-carbamo...)

IC50: 1.00E+3nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109306(CHEMBL139389 | [5-({[4-(1H-Benzoimidazol-2-yl)-thi...)

IC50: 1.00E+3nMAssay Description:Adhesion of recombinant alphaV-beta3 integrin expressed in CHO-K1 to osteopontin (OPN)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109311((5-{[4-(1H-Benzoimidazol-2-yl)-phenylcarbamoyl]-me...)

IC50: 5.00E+3nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109295((6-Oxo-5-{[4-(pyridin-2-ylamino)-benzylcarbamoyl]-...)

IC50: 5.00E+3nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109308(CHEMBL138242 | {5-[(4-Benzyloxycarbonylamino-benzy...)

IC50: 1.00E+4nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109288((5-{4-[4-(3-Benzyl-ureido)-phenyl]-butyl}-6-oxo-6,...)

IC50: 1.00E+4nMAssay Description:Cell adhesion of alphaV-beta3 integrin expressed in CHO-K1 cell to osteopontin (OPN)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109294((5-{[3-(1H-Benzoimidazol-2-yl)-benzylcarbamoyl]-me...)

IC50: 1.00E+4nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109292(CHEMBL136142 | {5-[(4-Benzylcarbamoyloxy-benzylcar...)

IC50: 1.00E+4nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid

Details Article PubMed

Integrin alpha-IIb/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109298(CHEMBL344162 | [5-({[4-(1H-Benzoimidazol-2-ylamino...)

IC50: 1.00E+6nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Integrin alpha-IIb/beta-3(Human)
Knoll

Curated by ChEMBL

BDBM50109296((5-{[4-(1H-Benzoimidazol-2-ylamino)-benzylcarbamoy...)

IC50: 1.00E+6nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed