Compile Data Set for Download or QSAR
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Found 12 Enz. Inhib. hit(s) with all data for entry = 788
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM6143(8-[(2-bromo-4-chloro-5-methoxyphenyl)amino]-3-[2-(...)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM6134(8-[(2-bromo-4-chloro-5-methoxyphenyl)amino]-3H-imi...)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM6142(8-[(4-chloro-5-methoxy-2-methylphenyl)amino]-3-[2-...)
Affinity DataIC50:  29nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM6135(8-[(2-chloro-5-methoxyphenyl)amino]-3H-imidazo[4,5...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM6140(8-[(2-chloro-5-methoxyphenyl)amino]-3-[2-(morpholi...)
Affinity DataIC50:  43nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM6138(8-[(5-methoxy-2-methylphenyl)amino]-2-{[2-(morphol...)
Affinity DataIC50:  67nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM6133(8-[(2-bromo-4-chlorophenyl)amino]-3H-imidazo[4,5-g...)
Affinity DataIC50:  75nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM6141(8-[(5-methoxy-2-methylphenyl)amino]-3-[2-(morpholi...)
Affinity DataIC50:  120nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM6137(2-{[2-(morpholin-4-yl)ethyl]amino}-8-[(3,4,5-trime...)
Affinity DataIC50:  180nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM6144(3-[2-(morpholin-4-yl)ethyl]-8-[(3,4,5-trimethoxyph...)
Affinity DataIC50:  200nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM6136(8-[(3,4,5-trimethoxyphenyl)amino]-3H-imidazo[4,5-g...)
Affinity DataIC50:  330nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM6139(2-(morpholin-4-ylmethyl)-8-[(3,4,5-trimethoxypheny...)
Affinity DataIC50:  620nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed