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Report error Found 89 Enz. Inhib. hit(s) with all data for entry = 50017797
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50137196(6-Phenyl-thieno[3,2-d]pyrimidin-4-ylamine | CHEMBL...)
Affinity DataIC50:  970nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26098(3-amino-5-(thiophen-3-yl)thiophene-2-carboxamide |...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186653(CHEMBL207238 | amino-4-(4-carbamoyl-phenoxymethyl)...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186637(3-(3-methyl-ureido)-5-phenyl-thiophene-2-carboxyli...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186655(2-amino-5-phenylthiophene-3-carboxamide | CHEMBL38...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186618(3-amino-5-(4-fluoro-phenyl)-thiophene-2-carboxylic...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186624(3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carbox...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186660(3-amino-6-butyl-4-methyl-thieno[2,3-b]pyridine-2-c...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186618(3-amino-5-(4-fluoro-phenyl)-thiophene-2-carboxylic...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186624(3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carbox...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of IKK alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186614(3-amino-5-(4-methoxyphenyl)thiophene-2-carboxamide...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186636(3-amino-6-tert-butyl-2-carbamoyl-thieno[2,3-b]pyri...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C19(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186618(3-amino-5-(4-fluoro-phenyl)-thiophene-2-carboxylic...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase BTK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186624(3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carbox...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186652(3-amino-6-isobutyl-4-methyl-thieno[2,3-b]pyridine-...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186635(5-amino-2-benzthiophene-2-yl-oxazole-4-carboxylic ...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186645(5-amino-2-thiophen-3-yl-oxazole-4-carboxylic acid ...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186656(5-(4-fluoro-phenyl)-3-methylamino-thiophene-2-carb...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186639(4-(4-cyano-phenoxymethyl)-6-methyl-thieno[2,3-b]py...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186631(5-amino-2-(4-tert-butyl-phenyl)-oxazole-4-carboxyl...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186651(5-amino-2-(2-methyl-phenyl)-oxazole-4-carboxylic a...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186644(5-amino-2-(2-chloro-phenyl)-oxazole-4-carboxylic a...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186632(3-amino-5-(4-chlorophenyl)thiophene-2-carboxamide ...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186618(3-amino-5-(4-fluoro-phenyl)-thiophene-2-carboxylic...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186625(3-amino-thieno[2,3-b]pyridine-2-carboxylic acid am...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186633(5-amino-2-(4-trifluoromethyl-phenyl)-oxazole-4-car...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186647(3-amino-6-methyl-4-phenoxymethyl-thieno[2,3-b]pyri...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186621(2-amino-quinoline-3-carboxylic acid amide | CHEMBL...)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186617(5-phenyl-3-propionylamino-thiophene-2-carboxylic a...)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186622(5-amino-2-(3-chloro-phenyl)-oxazole-4-carboxylic a...)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186616(5-amino-2-phenyl-oxazole-4-carboxylic acid amide |...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186618(3-amino-5-(4-fluoro-phenyl)-thiophene-2-carboxylic...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186634(3-amino-benzo[b]thiophene-2-carboxylic acid amide ...)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186628(5-amino-2-p-tolyl-oxazole-4-carboxylic acid amide ...)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186650(3-amino-4-(hydroxymethyl)-6-methylthieno[2,3-b]pyr...)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186654(4-(4-methoxy-phenoxymethyl)-6-methyl-thieno[2,3-b]...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186657(5-amino-2-(4-chloro-phenyl)-oxazole-4-carboxylic a...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186638(5-amino-2-(3-methoxy-phenyl)-oxazole-4-carboxylic ...)
Affinity DataIC50:  1.39E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM27462(2-amino-5-phenylbenzamide | Amino-substituted benz...)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186626(3-amino-2-carbamoyl-6-methyl-thieno[2,3-b]pyridine...)
Affinity DataIC50:  1.51E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase BTK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50:  1.51E+4nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM114965(6-phenyl-1H-thieno[3,2-d]pyrimidin-4-one | CHEMBL3...)
Affinity DataIC50: >1.55E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186623(5-amino-2-(4-methoxy-phenyl)-oxazole-4-carboxylic ...)
Affinity DataIC50:  1.77E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186640(3-amino-5-methyl-thieno[2,3-b]pyridine-2-carboxyli...)
Affinity DataIC50:  1.99E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186625(3-amino-thieno[2,3-b]pyridine-2-carboxylic acid am...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of IKK alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186659(3-dimethylamino-5-(4-fluoro-phenyl)-thiophene-2-ca...)
Affinity DataIC50: >2.35E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186618(3-amino-5-(4-fluoro-phenyl)-thiophene-2-carboxylic...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of IKK alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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