Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50019974
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209260BDBM50209260((S)-1-(5-chloronaphthalen-2-ylsulfonyl)-N-methyl-N...)
Affinity DataKi:  100nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209260BDBM50209260((S)-1-(5-chloronaphthalen-2-ylsulfonyl)-N-methyl-N...)
Affinity DataKi:  150nMAssay Description:Displacement of mouse MDC from recombinant CCR4 receptor expressed in CHO cells coexpressing G-alpha-16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209278BDBM50209278((S)-N-(1-(2-carbamoylphenethyl)piperidin-4-yl)-1-(...)
Affinity DataKi:  240nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209261BDBM50209261((S)-N-(1-(2-fluorophenethyl)piperidin-4-yl)-1-(5-c...)
Affinity DataKi:  260nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209251BDBM50209251((S)-N-(1-(2-aminophenethyl)piperidin-4-yl)-1-(5-ch...)
Affinity DataKi:  280nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209257BDBM50209257((S)-N-(1-(3-chlorophenethyl)piperidin-4-yl)-1-(5-c...)
Affinity DataKi:  400nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209279BDBM50209279((S)-N-(1-(2-(trifluoromethyl)phenethyl)piperidin-4...)
Affinity DataKi:  420nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209262BDBM50209262((S)-N-(1-(2-chlorophenethyl)piperidin-4-yl)-1-(5-c...)
Affinity DataKi:  460nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209265BDBM50209265((S)-N-(1-(3-methoxyphenethyl)piperidin-4-yl)-1-(5-...)
Affinity DataKi:  470nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209260BDBM50209260((S)-1-(5-chloronaphthalen-2-ylsulfonyl)-N-methyl-N...)
Affinity DataKi:  500nMAssay Description:Displacement of human MDC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209253BDBM50209253((S)-2-(2-(4-(1-(5-chloronaphthalen-2-ylsulfonyl)-N...)
Affinity DataKi:  530nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209268BDBM50209268((S)-N-methyl-1-(naphthalen-2-ylsulfonyl)-N-(1-phen...)
Affinity DataKi:  590nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209255BDBM50209255((S)-N-methyl-1-(naphthalen-2-ylsulfonyl)-N-(1-(3-p...)
Affinity DataKi:  620nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209258BDBM50209258((S)-N-(1-(4-chlorophenethyl)piperidin-4-yl)-1-(5-c...)
Affinity DataKi:  820nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209269BDBM50209269((S)-1-(5-fluoronaphthalen-2-ylsulfonyl)-N-methyl-N...)
Affinity DataKi:  850nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209263BDBM50209263((S)-N-(1-benzylpiperidin-4-yl)-N-methyl-1-(naphtha...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209281BDBM50209281((S)-1-(5-chloronaphthalen-2-ylsulfonyl)-N-ethyl-N-...)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209270BDBM50209270((S)-N-(1-benzylpiperidin-4-yl)-1-(naphthalen-2-yls...)
Affinity DataKi:  4.60E+3nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209252BDBM50209252((S)-1-(5-chloronaphthalen-2-ylsulfonyl)-N-methyl-N...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209272BDBM50209272((S)-1-(naphthalen-2-ylsulfonyl)-N-(1-(pyridin-2-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209256BDBM50209256((S)-N-(1-benzylpiperidin-4-yl)-1-(4-isopropylpheny...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209271BDBM50209271((S)-2-(1-(naphthalen-2-ylsulfonyl)-N-(1-phenethylp...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209274BDBM50209274((S)-N-(2-morpholinoethyl)-1-(naphthalen-2-ylsulfon...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209273BDBM50209273((S)-1-(5-acetamidonaphthalen-2-ylsulfonyl)-N-methy...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209275BDBM50209275((S)-N-(1-isobutylpiperidin-4-yl)-1-(naphthalen-2-y...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of human MDC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209246BDBM50209246((S)-1-(naphthalen-2-ylsulfonyl)-N-(1-(pyridin-3-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209248BDBM50209248((S)-ethyl 2-(1-(naphthalen-2-ylsulfonyl)-N-(1-phen...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209247BDBM50209247((S)-1-(5-aminonaphthalen-2-ylsulfonyl)-N-methyl-N-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209250BDBM50209250((S)-N-methyl-1-(naphthalen-2-ylsulfonyl)-N-(1-(phe...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209249BDBM50209249((S)-N-(1-benzylpiperidin-4-yl)-1-(benzylsulfonyl)p...)
Affinity DataKi:  1.50E+4nMAssay Description:Displacement of human MDC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209266BDBM50209266((S)-N2-(1-benzylpiperidin-4-yl)-N1-(4-tert-butylph...)
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209277BDBM50209277((R)-N-(1-benzylpiperidin-4-yl)-1-(naphthalen-2-yls...)
Affinity DataKi:  2.02E+4nMAssay Description:Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209276BDBM50209276((S)-N-(1-benzylpiperidin-4-yl)-1-(naphthalen-2-ylm...)
Affinity DataKi:  2.50E+4nMAssay Description:Displacement of human MDC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209264BDBM50209264((S)-N-(1-benzylpiperidin-4-yl)-N-methyl-1-(naphtha...)
Affinity DataKi:  2.60E+4nMAssay Description:Displacement of human MDC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209259BDBM50209259((S)-N-(1-benzylpiperidin-4-yl)-1-(phenylsulfonyl)p...)
Affinity DataKi: >2.90E+4nMAssay Description:Displacement of human MDC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209267BDBM50209267((S)-1-(2-naphthoyl)-N-(1-benzylpiperidin-4-yl)pyrr...)
Affinity DataKi: >2.90E+4nMAssay Description:Displacement of human MDC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209280BDBM50209280((S)-N-(1-benzylpiperidin-4-yl)-1-(isopropylsulfony...)
Affinity DataKi: >2.90E+4nMAssay Description:Displacement of human MDC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209254BDBM50209254((S)-1-(naphthalen-2-ylsulfonyl)-N-(piperidin-4-yl)...)
Affinity DataKi: >3.30E+4nMAssay Description:Displacement of human MDC from recombinant CCR4 receptor expressed in CHO cells co-expressing Galpha16 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed