Compile Data Set for Download or QSAR
maximum 50k data
Found 38 Enz. Inhib. hit(s) with all data for entry = 50034403
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50335512(1-(4-(5-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl...)
Affinity DataEC50:  1.21E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361879(CHEMBL1938925)
Affinity DataEC50:  570nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361877(CHEMBL1938923)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361878(CHEMBL1938924)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361879(CHEMBL1938925)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361880(CHEMBL1938926)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361881(CHEMBL1938927)
Affinity DataEC50:  2.06E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361881(CHEMBL1938927)
Affinity DataEC50:  2.06E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361882(CHEMBL1938928)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361883(CHEMBL1938929)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361884(CHEMBL1938930)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361885(CHEMBL1938931)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361886(CHEMBL1938932)
Affinity DataEC50:  7.42E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361887(CHEMBL1938933)
Affinity DataEC50:  2.04E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361888(CHEMBL1938934)
Affinity DataEC50:  6.24E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361888(CHEMBL1938934)
Affinity DataEC50:  6.24E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361889(CHEMBL1938935)
Affinity DataEC50:  900nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361890(CHEMBL1938936)
Affinity DataEC50:  2.68E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50335514(1-((3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,...)
Affinity DataEC50:  888nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50335512(1-(4-(5-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl...)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361876(CHEMBL1938922)
Affinity DataEC50:  680nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361877(CHEMBL1938923)
Affinity DataEC50:  2.37E+3nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361878(CHEMBL1938924)
Affinity DataEC50:  1.96E+3nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361880(CHEMBL1938926)
Affinity DataEC50:  240nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361881(CHEMBL1938927)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361881(CHEMBL1938927)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361882(CHEMBL1938928)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361883(CHEMBL1938929)
Affinity DataEC50:  1.17E+3nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361884(CHEMBL1938930)
Affinity DataEC50:  2.72E+3nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361885(CHEMBL1938931)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361886(CHEMBL1938932)
Affinity DataEC50:  2.71E+3nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361887(CHEMBL1938933)
Affinity DataEC50:  42nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361888(CHEMBL1938934)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361888(CHEMBL1938934)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361889(CHEMBL1938935)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361890(CHEMBL1938936)
Affinity DataEC50:  430nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50335514(1-((3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50361876(CHEMBL1938922)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed