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Found 9 Enz. Inhib. hit(s) with all data for entry = 50042311
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423883(CHEMBL2312430)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423885(CHEMBL2312431)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423886(CHEMBL2312428)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423888(CHEMBL2312414)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423887(CHEMBL2312415)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50268295(2-Cyano-N-octyl-3-(1-(3-dimethylaminopropyl)-1H-in...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423883(CHEMBL2312430)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of rat full length His6-tagged dyn2 using phosphotidylserine as substrate after 90 mins by malachite green GTPase assay in presence of GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423884(CHEMBL2312432)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50268295(2-Cyano-N-octyl-3-(1-(3-dimethylaminopropyl)-1H-in...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of rat full length His6-tagged dyn2 using phosphotidylserine as substrate after 90 mins by malachite green GTPase assay in presence of GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed