Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50046575
LigandPNGBDBM50119621(CHEMBL3618245)
Affinity DataKi:  0.600nMAssay Description:Inhibition of PI3Kdelta (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119621(CHEMBL3618245)
Affinity DataKi:  5.30nMAssay Description:Inhibition of PI3Kgamma (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119613(CHEMBL3618237)
Affinity DataKi:  5.60nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119614(CHEMBL3618238)
Affinity DataKi:  5.70nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119619(CHEMBL3618243)
Affinity DataKi:  6.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119617(CHEMBL3618241)
Affinity DataKi:  6.30nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119616(CHEMBL3618240)
Affinity DataKi:  6.5nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119618(CHEMBL3618242)
Affinity DataKi:  8.30nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119621(CHEMBL3618245)
Affinity DataKi:  11nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119609(CHEMBL3618233)
Affinity DataKi:  14nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119621(CHEMBL3618245)
Affinity DataKi:  17nMAssay Description:Inhibition of PI3Kbeta (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119620(CHEMBL3618244)
Affinity DataKi:  26nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119606(CHEMBL3618231)
Affinity DataKi:  29nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119612(CHEMBL3618236)
Affinity DataKi:  43nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119615(CHEMBL3618239)
Affinity DataKi:  43nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119611(CHEMBL3618235)
Affinity DataKi:  54nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119608(CHEMBL3618232)
Affinity DataKi:  148nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119610(CHEMBL3618234)
Affinity DataKi:  529nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50119612(CHEMBL3618236)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119621(CHEMBL3618245)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in AKT Ser473 phosphorylation incubated for 2 hrs followed by compound wahout by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50119611(CHEMBL3618235)
Affinity DataIC50:  12nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50119613(CHEMBL3618237)
Affinity DataIC50:  16nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119612(CHEMBL3618236)
Affinity DataIC50:  18nMAssay Description:Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in AKT Ser473 phosphorylation incubated for 2 hrs followed by compound wahout by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50119615(CHEMBL3618239)
Affinity DataIC50:  20nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119619(CHEMBL3618243)
Affinity DataIC50:  20nMAssay Description:Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in AKT Ser473 phosphorylation incubated for 2 hrs followed by compound wahout by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119617(CHEMBL3618241)
Affinity DataIC50:  26nMAssay Description:Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in AKT Ser473 phosphorylation incubated for 2 hrs followed by compound wahout by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119613(CHEMBL3618237)
Affinity DataIC50:  32nMAssay Description:Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in AKT Ser473 phosphorylation incubated for 2 hrs followed by compound wahout by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50119618(CHEMBL3618242)
Affinity DataIC50:  34nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119618(CHEMBL3618242)
Affinity DataIC50:  34nMAssay Description:Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in AKT Ser473 phosphorylation incubated for 2 hrs followed by compound wahout by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50119620(CHEMBL3618244)
Affinity DataIC50:  36nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50119606(CHEMBL3618231)
Affinity DataIC50:  37nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119606(CHEMBL3618231)
Affinity DataIC50:  40nMAssay Description:Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in AKT Ser473 phosphorylation incubated for 2 hrs followed by compound wahout by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119614(CHEMBL3618238)
Affinity DataIC50:  41nMAssay Description:Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in AKT Ser473 phosphorylation incubated for 2 hrs followed by compound wahout by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119620(CHEMBL3618244)
Affinity DataIC50:  45nMAssay Description:Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in AKT Ser473 phosphorylation incubated for 2 hrs followed by compound wahout by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50119608(CHEMBL3618232)
Affinity DataIC50:  57nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50119614(CHEMBL3618238)
Affinity DataIC50:  62nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119615(CHEMBL3618239)
Affinity DataIC50:  69nMAssay Description:Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in AKT Ser473 phosphorylation incubated for 2 hrs followed by compound wahout by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119609(CHEMBL3618233)
Affinity DataIC50:  86nMAssay Description:Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in AKT Ser473 phosphorylation incubated for 2 hrs followed by compound wahout by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50119617(CHEMBL3618241)
Affinity DataIC50:  121nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50119619(CHEMBL3618243)
Affinity DataIC50:  157nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50119609(CHEMBL3618233)
Affinity DataIC50:  198nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50119621(CHEMBL3618245)
Affinity DataIC50:  206nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119608(CHEMBL3618232)
Affinity DataIC50:  229nMAssay Description:Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in AKT Ser473 phosphorylation incubated for 2 hrs followed by compound wahout by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50119610(CHEMBL3618234)
Affinity DataIC50:  277nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119616(CHEMBL3618240)
Affinity DataIC50:  294nMAssay Description:Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in AKT Ser473 phosphorylation incubated for 2 hrs followed by compound wahout by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50119616(CHEMBL3618240)
Affinity DataIC50:  412nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50119610(CHEMBL3618234)
Affinity DataIC50: >780nMAssay Description:Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in AKT Ser473 phosphorylation incubated for 2 hrs followed by compound wahout by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed