Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50006510
TargetBeta-3 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500480(CHEMBL3747546)
Affinity DataEC50:  0.490nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as reduction in cAMP level after 30 mins by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50338821(2-(2-aminothiazol-4-yl)-N-(4-(((2S,5R)-5-((R)-hydr...)
Affinity DataEC50:  0.980nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as reduction in cAMP level after 30 mins by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500479(CHEMBL3747356)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as reduction in cAMP level after 30 mins by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500481(CHEMBL3746280)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as reduction in cAMP level after 30 mins by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500477(CHEMBL3747455)
Affinity DataEC50:  3.10nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as reduction in cAMP level after 30 mins by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500475(CHEMBL3747244)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as reduction in cAMP level after 30 mins by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500473(CHEMBL3745911)
Affinity DataEC50:  3.70nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as reduction in cAMP level after 30 mins by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500478(CHEMBL3745890)
Affinity DataEC50:  5.40nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as reduction in cAMP level after 30 mins by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500476(CHEMBL3747710)
Affinity DataEC50:  9.70nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as reduction in cAMP level after 30 mins by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500472(CHEMBL3746068)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as reduction in cAMP level after 30 mins by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500474(CHEMBL3747487)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as reduction in cAMP level after 30 mins by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500471(CHEMBL3746885)
Affinity DataEC50:  75nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as reduction in cAMP level after 30 mins by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500472(CHEMBL3746068)
Affinity DataIC50: 5.20E+3nMAssay Description:Displacement of [125I]CYP from human beta-2 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500475(CHEMBL3747244)
Affinity DataIC50: 5.60E+3nMAssay Description:Displacement of [125I]CYP from human beta-2 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500480(CHEMBL3747546)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human ERG by IKr binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500474(CHEMBL3747487)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human ERG by IKr binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500474(CHEMBL3747487)
Affinity DataIC50: 1.09E+4nMAssay Description:Displacement of [125I]CYP from human beta-2 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500481(CHEMBL3746280)
Affinity DataIC50: 1.10E+4nMAssay Description:Displacement of [125I]CYP from human beta-2 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500471(CHEMBL3746885)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human ERG by IKr binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500480(CHEMBL3747546)
Affinity DataIC50: 1.34E+4nMAssay Description:Displacement of [125I]CYP from human beta-2 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500478(CHEMBL3745890)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human ERG by IKr binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500477(CHEMBL3747455)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-2 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500480(CHEMBL3747546)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-1 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500475(CHEMBL3747244)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-1 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500479(CHEMBL3747356)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-1 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500481(CHEMBL3746280)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-1 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500479(CHEMBL3747356)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-2 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500478(CHEMBL3745890)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-2 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500477(CHEMBL3747455)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-1 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500476(CHEMBL3747710)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-1 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500476(CHEMBL3747710)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-2 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500478(CHEMBL3745890)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-1 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500471(CHEMBL3746885)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-1 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500474(CHEMBL3747487)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-1 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500471(CHEMBL3746885)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-2 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500472(CHEMBL3746068)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-1 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500472(CHEMBL3746068)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG by IKr binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500481(CHEMBL3746280)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human ERG by IKr binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500477(CHEMBL3747455)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of human ERG by IKr binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500475(CHEMBL3747244)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of human ERG by IKr binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500479(CHEMBL3747356)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of human ERG by IKr binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500476(CHEMBL3747710)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human ERG by IKr binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed