BindingDB PrimarySearch

Found 14 Enz. Inhib. hit(s) with all data for entry = 50002601

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)

Curated by ChEMBL

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)

IC50: 2.5nMAssay Description:Inhibition of human recombinant PI3K-deltaMore data for this Ligand-Target Pair

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3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)

Curated by ChEMBL

BDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)

IC50: 130nMAssay Description:Inhibition of PI3K-delta (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10 mins in presence of [gamma-32P]ATP by radioliga...More data for this Ligand-Target Pair

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3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)

Curated by ChEMBL

BDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)

IC50: 160nMAssay Description:Inhibition of PI3K-delta (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)

Curated by ChEMBL

BDBM50460339(CHEMBL4229035)

IC50: 1.00E+3nMAssay Description:Inhibition of PI3K-gamma (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)

Curated by ChEMBL

BDBM50460340(CHEMBL4228200)

IC50: 3.00E+3nMAssay Description:Inhibition of PI3K-gamma (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)

Curated by ChEMBL

BDBM50460339(CHEMBL4229035)

IC50: 5.00E+3nMAssay Description:Inhibition of PI3K-delta (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)

Curated by ChEMBL

BDBM50460340(CHEMBL4228200)

IC50: 1.00E+4nMAssay Description:Inhibition of PI3K-delta (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)

Curated by ChEMBL

BDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)

IC50: 7.00E+4nMAssay Description:Inhibition of PI3K-gamma (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)

Curated by ChEMBL

BDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)

IC50: 2.00E+5nMAssay Description:Inhibition of PI3K-beta (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)

Curated by ChEMBL

BDBM50460339(CHEMBL4229035)

IC50: 2.50E+5nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)

Curated by ChEMBL

BDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)

IC50: 2.55E+5nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)

Curated by ChEMBL

BDBM50460340(CHEMBL4228200)

IC50: 2.90E+5nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)

Curated by ChEMBL

BDBM50460340(CHEMBL4228200)

IC50: 3.55E+5nMAssay Description:Inhibition of PI3K-beta (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)

Curated by ChEMBL

BDBM50460339(CHEMBL4229035)

IC50: 4.30E+5nMAssay Description:Inhibition of PI3K-beta (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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