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Found 27 Enz. Inhib. hit(s) with all data for entry = 50002704
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461792(CHEMBL4226027)
Affinity DataEC50:  2.80E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461815(CHEMBL4227806)
Affinity DataEC50:  1.80E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461794(Formula 405 | Pregnenolone | Pregnenolone Succinat...)
Affinity DataEC50:  2.76E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461795(CHEMBL4228540)
Affinity DataEC50:  1.90E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461796(CHEMBL4224777)
Affinity DataEC50:  8.50E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461797(CHEMBL4228864)
Affinity DataEC50:  9.90E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461798(CHEMBL4224832)
Affinity DataEC50:  9.90E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461799(CHEMBL4228607)
Affinity DataEC50:  1.72E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461800(CHEMBL4225347)
Affinity DataEC50:  7.40E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461801(CHEMBL4229097)
Affinity DataEC50:  5.20E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461802(CHEMBL4228274)
Affinity DataEC50:  8.24E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461803(CHEMBL4225041)
Affinity DataEC50:  3.82E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461804(CHEMBL4224833)
Affinity DataEC50:  1.61E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461796(CHEMBL4224777)
Affinity DataEC50:  8.90E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2A receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461796(CHEMBL4224777)
Affinity DataEC50:  1.04E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2C receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461805(CHEMBL4225172)
Affinity DataEC50:  1.09E+5nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461806(CHEMBL4225836)
Affinity DataEC50:  4.70E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461807(CHEMBL4228317)
Affinity DataEC50:  4.91E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461796(CHEMBL4224777)
Affinity DataEC50:  1.30E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2D receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461808(CHEMBL4226487)
Affinity DataEC50:  1.51E+5nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461809(CHEMBL4224866)
Affinity DataEC50:  1.07E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461810(CHEMBL4228410)
Affinity DataEC50:  3.98E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461811(CHEMBL4224852)
Affinity DataEC50:  4.86E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461812(CHEMBL4225526)
Affinity DataEC50:  1.93E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461813(CHEMBL4224980)
Affinity DataEC50:  2.62E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461814(CHEMBL4228835)
Affinity DataEC50:  1.80E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Institute Of Physiology Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50461793(CHEMBL4225324)
Affinity DataEC50:  2.17E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed