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Report error Found 71 Enz. Inhib. hit(s) with all data for entry = 50002482
TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459080(CHEMBL4211423)
Affinity DataKi:  21nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459060(CHEMBL4208530)
Affinity DataKi:  41nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459079(CHEMBL4206764)
Affinity DataKi:  42nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459072(CHEMBL4215861)
Affinity DataKi:  42nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459071(CHEMBL4204195)
Affinity DataKi:  43nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459059(CHEMBL4217043)
Affinity DataKi:  53nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459055(CHEMBL4207715)
Affinity DataKi:  88nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459068(CHEMBL4212068)
Affinity DataKi:  108nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459053(CHEMBL4208241)
Affinity DataKi:  156nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459078(CHEMBL4216516)
Affinity DataKi:  166nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459054(CHEMBL4213248)
Affinity DataKi:  183nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459073(CHEMBL4203654)
Affinity DataKi:  228nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459070(CHEMBL4216389)
Affinity DataKi:  315nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459074(Upamostat | Wx-671)
Affinity DataKi:  410nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459064(CHEMBL4203547)
Affinity DataKi:  508nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459077(CHEMBL4210813)
Affinity DataKi:  658nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459052(CHEMBL4211642)
Affinity DataKi:  884nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459063(CHEMBL4218928)
Affinity DataKi:  934nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459057(CHEMBL4203367)
Affinity DataKi:  1.03E+3nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459058(CHEMBL4207061)
Affinity DataKi:  1.32E+3nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataKi:  1.36E+3nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Mouse)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459059(CHEMBL4217043)
Affinity DataKi:  1.61E+3nMAssay Description:Inhibition of mouse uPA using Z-Gly-Gly-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459067(CHEMBL4204836)
Affinity DataKi:  1.78E+3nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Mouse)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459054(CHEMBL4213248)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of mouse uPA using Z-Gly-Gly-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459069(CHEMBL4211937)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Mouse)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM16173(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)
Affinity DataKi:  2.31E+3nMAssay Description:Inhibition of mouse uPA using Z-Gly-Gly-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459066(CHEMBL4212621)
Affinity DataKi:  2.42E+3nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM16173(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)
Affinity DataKi:  2.43E+3nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459075(CHEMBL4208316)
Affinity DataKi:  3.31E+3nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459056(CHEMBL4215225)
Affinity DataKi:  3.54E+3nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459076(CHEMBL4203024)
Affinity DataKi:  4.26E+3nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459061(CHEMBL4207379)
Affinity DataKi:  5.02E+3nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459065(CHEMBL4215760)
Affinity DataKi:  5.67E+3nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM16173(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of uPA (unknown origin) using L-pyroglutamyl-glycyl-L-arginine-p-nitro-anilide as susbtrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetUrokinase-type plasminogen activator(Mouse)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataKi:  9.31E+3nMAssay Description:Inhibition of mouse uPA using Z-Gly-Gly-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459062(CHEMBL4212269)
Affinity DataKi:  1.64E+4nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50147093(6-Carbamimidoyl-4-(pyrimidin-2-ylamino)-naphthalen...)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459059(CHEMBL4217043)
Affinity DataIC50:  39nMAssay Description:Inhibition of human kidney uPA using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459055(CHEMBL4207715)
Affinity DataIC50:  430nMAssay Description:Inhibition of human kidney uPA using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459054(CHEMBL4213248)
Affinity DataIC50:  530nMAssay Description:Inhibition of human kidney uPA using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human kidney uPA using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of thrombin (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTrypsin(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of trypsin (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459054(CHEMBL4213248)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of thrombin (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetPlasminogen(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of plasmin (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTissue-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459054(CHEMBL4213248)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of tPA (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetTrypsin(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459054(CHEMBL4213248)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of trypsin (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetPlasminogen(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459054(CHEMBL4213248)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of plasmin (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetTissue-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of tPA (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlasma kallikrein(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459054(CHEMBL4213248)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of human plasma kallikrein using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

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