Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 50004197
TargetCytochrome P450 2C9(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501822(CHEMBL4587127)
Affinity DataIC50:  3.38E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate preincubated for 5 mins followed by NADPH-generating system addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501820(CHEMBL4528087)
Affinity DataIC50:  3.93E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate preincubated for 5 mins followed by NADPH-generating system addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501823(CHEMBL3261573)
Affinity DataIC50:  5.35E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate preincubated for 5 mins followed by NADPH-generating system addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501822(CHEMBL4587127)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate preincubated for 5 mins followed by NADPH-generating system addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501823(CHEMBL3261573)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins followed by NADPH-generating system addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501821(CHEMBL4582168)
Affinity DataIC50:  2.05E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate preincubated for 5 mins followed by NADPH-generating system addition an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501823(CHEMBL3261573)
Affinity DataIC50:  2.14E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using tolbutamide as substrate preincubated for 5 mins followed by NADPH-generating system addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501822(CHEMBL4587127)
Affinity DataIC50:  2.36E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins followed by NADPH-generating system addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501820(CHEMBL4528087)
Affinity DataIC50:  2.41E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using tolbutamide as substrate preincubated for 5 mins followed by NADPH-generating system addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501820(CHEMBL4528087)
Affinity DataIC50:  2.94E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins followed by NADPH-generating system addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501823(CHEMBL3261573)
Affinity DataIC50:  3.39E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins followed by NADPH-generating system addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501820(CHEMBL4528087)
Affinity DataIC50:  3.69E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins followed by NADPH-generating system addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501822(CHEMBL4587127)
Affinity DataIC50:  3.77E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins followed by NADPH-generating system addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501822(CHEMBL4587127)
Affinity DataIC50:  3.81E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using tolbutamide as substrate preincubated for 5 mins followed by NADPH-generating system addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501820(CHEMBL4528087)
Affinity DataIC50:  3.97E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate preincubated for 5 mins followed by NADPH-generating system addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501821(CHEMBL4582168)
Affinity DataIC50:  4.96E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using tolbutamide as substrate preincubated for 5 mins followed by NADPH-generating system addition an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501821(CHEMBL4582168)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins followed by NADPH-generating system addition and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501822(CHEMBL4587127)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by NADPH-generating system addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501823(CHEMBL3261573)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by NADPH-generating system addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501820(CHEMBL4528087)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by NADPH-generating system addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501821(CHEMBL4582168)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins followed by NADPH-generating system addition and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501821(CHEMBL4582168)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate preincubated for 5 mins followed by NADPH-generating system addition and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501823(CHEMBL3261573)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate preincubated for 5 mins followed by NADPH-generating system addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501821(CHEMBL4582168)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by NADPH-generating system addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyoferlin(Homo sapiens)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50501821(CHEMBL4582168)
Affinity DataKd:  94nMAssay Description:Reversible binding affinity to recombinant human GST-tagged MYOF C2 domain (3445 to 3912 residues) expressed in Escherichia coli BL21 (DE3) by surfac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed