Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50010582
TargetAdenosylhomocysteinase(Rattus norvegicus)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50006222((1S,2R,5R)-5-(6-Amino-purin-9-yl)-3-hydroxymethyl-...)
Affinity DataKi:  8.40nMAssay Description:Reversible inhibition of rat liver S- adenosyl-L-homocysteine hydrolase using SAH as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine decarboxylase(Hafnia alvei)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50540321(CHEMBL4646127)
Affinity DataKi:  4.70E+5nMAssay Description:Time dependent inhibition of Hafnia alvei lysine decarboxylase using L-lysine by Kitz-Wilson analysisMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine decarboxylase(Hafnia alvei)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50540320(CHEMBL4640604)
Affinity DataKi:  6.30E+5nMAssay Description:Time dependent inhibition of Hafnia alvei lysine decarboxylase using L-lysine by Kitz-Wilson analysisMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50289703(Lumacaftor | VRT 826809 | VRT-826809 | VX 809 | VX...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin) assessed as reduction in amodiaquine N-deethylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50289703(Lumacaftor | VRT 826809 | VRT-826809 | VX 809 | VX...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin) assessed as reduction in diclofenac 4-hydroxylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed