Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50012952
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using phosphatidylinositol as substrate in presence of ATP by luciferase-luciferin-coupled chemiluminescence...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 114nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 115nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 157nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 159nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 185nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 186nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 204nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 243nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 504nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
