Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50014866
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580509(CHEMBL5083918 | US20240122876, Example 3)
Affinity DataIC50: 50nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580504(CHEMBL5091011)
Affinity DataIC50: 95nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323432(3-Amino-1-(3-((4,4-Difluorocyclohexyl)Methoxy)Phen...)
Affinity DataIC50: 103nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580510(CHEMBL5094849)
Affinity DataIC50: 124nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580501(CHEMBL5069771 | US20240122876, Example 9)
Affinity DataIC50: 132nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580501(CHEMBL5069771 | US20240122876, Example 9)
Affinity DataIC50: 132nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580499(CHEMBL5081450)
Affinity DataIC50: 145nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580511(CHEMBL5081640)
Affinity DataIC50: 169nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323415(3-Amino-1-(3-(cyclohexylmethoxy)Phenyl)Propan-1-Ol...)
Affinity DataIC50: 172nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580508(CHEMBL5094949 | US20240122876, Example 11)
Affinity DataIC50: 177nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580500(CHEMBL5077356 | US20240122876, Example 20)
Affinity DataIC50: 184nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580500(CHEMBL5077356 | US20240122876, Example 20)
Affinity DataIC50: 184nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323415(3-Amino-1-(3-(cyclohexylmethoxy)Phenyl)Propan-1-Ol...)
Affinity DataIC50: 190nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580503(CHEMBL5084662)
Affinity DataIC50: 201nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323432(3-Amino-1-(3-((4,4-Difluorocyclohexyl)Methoxy)Phen...)
Affinity DataIC50: 269nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580505(CHEMBL5083435 | US20240122876, Example 18)
Affinity DataIC50: 274nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580506(CHEMBL5092414)
Affinity DataIC50: 284nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580505(CHEMBL5083435 | US20240122876, Example 18)
Affinity DataIC50: 287nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580502(CHEMBL5086566)
Affinity DataIC50: 292nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50546390(CHEMBL4757869 | US20240122876, Example 2)
Affinity DataIC50: 323nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580507(CHEMBL5076106)
Affinity DataIC50: 358nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed