Found 8 Enz. Inhib. hit(s) with all data for entry = 50017436 TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 m...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 m...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 219nMAssay Description:Antagonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 259nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV holdi...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 266nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV holdi...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 m...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 m...More data for this Ligand-Target Pair
