Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50018579
LigandChemical structure of BindingDB Monomer ID 50609742BDBM50609742(CHEMBL5286106)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609728BDBM50609728(CHEMBL5267350)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609742BDBM50609742(CHEMBL5286106)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of LRRK2 in human PBMCs assessed as reduction in Ser95 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609741BDBM50609741(CHEMBL5284341)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 257207BDBM257207(US9493440, 51)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609741BDBM50609741(CHEMBL5284341)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609742BDBM50609742(CHEMBL5286106)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 257207BDBM257207(US9493440, 51)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609738BDBM50609738(CHEMBL5267690)
Affinity DataIC50: 2nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609738BDBM50609738(CHEMBL5267690)
Affinity DataIC50: 2nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609729BDBM50609729(CHEMBL5290520)
Affinity DataIC50: 3nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609728BDBM50609728(CHEMBL5267350)
Affinity DataIC50: 4nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609734BDBM50609734(CHEMBL5279615)
Affinity DataIC50: 4nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609733BDBM50609733(CHEMBL5282583)
Affinity DataIC50: 6nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609731BDBM50609731(CHEMBL5283154)
Affinity DataIC50: 14nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609737BDBM50609737(CHEMBL5266092)
Affinity DataIC50: 14nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609733BDBM50609733(CHEMBL5282583)
Affinity DataIC50: 18nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609734BDBM50609734(CHEMBL5279615)
Affinity DataIC50: 19nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609732BDBM50609732(CHEMBL5276834)
Affinity DataIC50: 21nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609729BDBM50609729(CHEMBL5290520)
Affinity DataIC50: 22nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609734BDBM50609734(CHEMBL5279615)
Affinity DataIC50: 24nMAssay Description:Inhibition of LRRK2 in human PBMCs assessed as reduction in Ser95 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609731BDBM50609731(CHEMBL5283154)
Affinity DataIC50: 24nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609737BDBM50609737(CHEMBL5266092)
Affinity DataIC50: 30nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609739BDBM50609739(CHEMBL5266616)
Affinity DataIC50: 35nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609732BDBM50609732(CHEMBL5276834)
Affinity DataIC50: 82nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 488343BDBM488343(US10954240, Example 47)
Affinity DataIC50: 100nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 488343BDBM488343(US10954240, Example 47)
Affinity DataIC50: 120nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609730BDBM50609730(CHEMBL5268380)
Affinity DataIC50: 161nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609735BDBM50609735(CHEMBL5275913)
Affinity DataIC50: 275nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609740BDBM50609740(CHEMBL5285084)
Affinity DataIC50: 300nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609739BDBM50609739(CHEMBL5266616)
Affinity DataIC50: 610nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609736BDBM50609736(CHEMBL5278535)
Affinity DataIC50: 990nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609740BDBM50609740(CHEMBL5285084)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50609730BDBM50609730(CHEMBL5268380)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed