Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50020181
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM530461(WO2022070069, Example 4 | N-(5-Chloro-3-methyl-1H-...)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of human DHODH using DHO and CoQ6 as substrate by DCIP dye based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM530462(WO2022070069, Example 5 | N-(5-Chloro-3-methyl-1H-...)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human DHODH using DHO and CoQ6 as substrate by DCIP dye based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM530459(WO2022070069, Example 2 | N-(2-Chloro-6-fluorophen...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human DHODH using DHO and CoQ6 as substrate by DCIP dye based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM530463(WO2022070069, Example 6 | (S)-N-(5-Chloro-3-methyl...)
Affinity DataIC50: 0.380nMAssay Description:Inhibition of human DHODH using DHO and CoQ6 as substrate by DCIP dye based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM530458(WO2022070069, Example 1 | N-(2-Chloro-6-fluorophen...)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of human DHODH using DHO and CoQ6 as substrate by DCIP dye based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM530460(WO2022070069, Example 3 | (S)-N-(2-Chloro-6-fluoro...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human DHODH using DHO and CoQ6 as substrate by DCIP dye based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed