Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50021930
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50646244(CHEMBL5594204)
Affinity DataIC50: 637nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as inhibition of LPS/nigericin-induced caspase-1 activationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50646243(CHEMBL5593379)
Affinity DataIC50: 786nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as inhibition of LPS/nigericin-induced caspase-1 activationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50646245(CHEMBL5595979)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as inhibition of LPS/nigericin-induced caspase-1 activationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50646247(CHEMBL5593017)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as inhibition of LPS/nigericin-induced caspase-1 activationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50646250(CHEMBL5595872)
Affinity DataIC50: 2.92E+3nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as inhibition of LPS/nigericin-induced caspase-1 activationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50646246(CHEMBL5593592)
Affinity DataIC50: 5.85E+3nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as inhibition of LPS/nigericin-induced caspase-1 activationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50646248(CHEMBL5595136)
Affinity DataIC50: 8.15E+3nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as inhibition of LPS/nigericin-induced caspase-1 activationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50646249(CHEMBL5594931)
Affinity DataIC50: 9.13E+3nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as inhibition of LPS/nigericin-induced caspase-1 activationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50646251(CHEMBL5595538)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as inhibition of LPS/nigericin-induced caspase-1 activationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed