Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50020084
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626063BDBM50626063(CHEMBL5414924)
Affinity DataIC50: 130nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626053BDBM50626053(CHEMBL5429161)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626055BDBM50626055(CHEMBL5401581)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626044BDBM50626044(CHEMBL5424691)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626048BDBM50626048(CHEMBL5407779)
Affinity DataIC50: 3.01E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626057BDBM50626057(CHEMBL5404529)
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626056BDBM50626056(CHEMBL5398679)
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50569607BDBM50569607(CHEMBL4846605)
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626050BDBM50626050(CHEMBL5411280)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626058BDBM50626058(CHEMBL5431684)
Affinity DataIC50: 3.96E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626046BDBM50626046(CHEMBL5407010)
Affinity DataIC50: 4.93E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626062BDBM50626062(CHEMBL5435953)
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626061BDBM50626061(CHEMBL5414723)
Affinity DataIC50: 5.95E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626060BDBM50626060(CHEMBL5395385)
Affinity DataIC50: 5.97E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626049BDBM50626049(CHEMBL5419637)
Affinity DataIC50: 5.97E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626052BDBM50626052(CHEMBL5411854)
Affinity DataIC50: 8.36E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626045BDBM50626045(CHEMBL5426512)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626047BDBM50626047(CHEMBL5439313)
Affinity DataIC50: 2.71E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626059BDBM50626059(CHEMBL5435228)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626051BDBM50626051(CHEMBL5420505)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626054BDBM50626054(CHEMBL5403247)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as reduction in LPS-stimulated IL-1beta level pretreated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed