Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50021861
TargetPolyphenol oxidase 4(Agaricus bisporus)
North-West University

Curated by ChEMBL
LigandPNGBDBM50559076(CHEMBL4743159)
Affinity DataIC50: 130nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosinase(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50559076(CHEMBL4743159)
Affinity DataIC50: 1.10E+3nMAssay Description:Competitive inhibition of human tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
North-West University

Curated by ChEMBL
LigandPNGBDBM31159(3-hydroxyquinolin-2(1H)-one, 13)
Affinity DataKi:  1.41E+3nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as inhibition constant by Lineweaver-Burk plots analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
North-West University

Curated by ChEMBL
LigandPNGBDBM50206007(3-hydroxy-2H-chromen-2-one | 3-Hydroxy-chromen-2-o...)
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
North-West University

Curated by ChEMBL
LigandPNGBDBM247013(US9701638, 4)
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
North-West University

Curated by ChEMBL
LigandPNGBDBM31148(3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
North-West University

Curated by ChEMBL
LigandPNGBDBM31151(3-hydroxyquinolin-2(1H)-one, 5)
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
North-West University

Curated by ChEMBL
LigandPNGBDBM31159(3-hydroxyquinolin-2(1H)-one, 13)
Affinity DataIC50: 6.11E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosinase(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50206007(3-hydroxy-2H-chromen-2-one | 3-Hydroxy-chromen-2-o...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
North-West University

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataIC50: 2.64E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
North-West University

Curated by ChEMBL
LigandPNGBDBM50645581(CHEMBL5591878)
Affinity DataIC50: 4.35E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
North-West University

Curated by ChEMBL
LigandPNGBDBM31156(3-hydroxyquinolin-2(1H)-one, 10)
Affinity DataIC50: 9.27E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
North-West University

Curated by ChEMBL
LigandPNGBDBM31158(3-hydroxyquinolin-2(1H)-one, 12)
Affinity DataIC50: 1.73E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
North-West University

Curated by ChEMBL
LigandPNGBDBM50645582(CHEMBL5589676)
Affinity DataIC50: 9.26E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed