Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50021846
TargetIndoleamine 2,3-dioxygenase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandPNGBDBM50138827(CHEMBL3752711 | US10233190, Example 1418)
Affinity DataIC50: 60nMAssay Description:Inhibition of human IDO1 using tryptophan as substrate assessed as reduction in N-formylkynurenine formation preincubated with compound for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandPNGBDBM50350248(CHEMBL1812545)
Affinity DataIC50: 300nMAssay Description:Inhibition of full length N-terminal/C-terminal his-tagged human TDO expressed in Escherichia coli BL21 (DE3) assessed as N-formylkynurenine formatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandPNGBDBM50138827(CHEMBL3752711 | US10233190, Example 1418)
Affinity DataIC50: 370nMAssay Description:Inhibition of full length N-terminal/C-terminal his-tagged human TDO expressed in Escherichia coli BL21 (DE3) assessed as N-formylkynurenine formatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567037(CHEMBL4851377)
Affinity DataIC50: 690nMAssay Description:Inhibition of full length N-terminal/C-terminal his-tagged human TDO expressed in Escherichia coli BL21 (DE3) assessed as N-formylkynurenine formatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567040(CHEMBL4875970)
Affinity DataIC50: 700nMAssay Description:Inhibition of full length N-terminal/C-terminal his-tagged human TDO expressed in Escherichia coli BL21 (DE3) assessed as N-formylkynurenine formatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567038(CHEMBL4863211)
Affinity DataIC50: 810nMAssay Description:Inhibition of full length N-terminal/C-terminal his-tagged human TDO expressed in Escherichia coli BL21 (DE3) assessed as N-formylkynurenine formatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567034(CHEMBL4853023)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of full length N-terminal/C-terminal his-tagged human TDO expressed in Escherichia coli BL21 (DE3) assessed as N-formylkynurenine formatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567036(CHEMBL4854488)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of full length N-terminal/C-terminal his-tagged human TDO expressed in Escherichia coli BL21 (DE3) assessed as N-formylkynurenine formatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567039(CHEMBL4860700)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of full length N-terminal/C-terminal his-tagged human TDO expressed in Escherichia coli BL21 (DE3) assessed as N-formylkynurenine formatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567035(CHEMBL4852682)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of full length N-terminal/C-terminal his-tagged human TDO expressed in Escherichia coli BL21 (DE3) assessed as N-formylkynurenine formatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 4.24E+5nMAssay Description:Inhibition of human TDO assessed as N-formylkynurenine formation using L-tryptophan as substrate by UV2100 spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed