Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50022733
TargetCarbonic anhydrase 7(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  2nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 12(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  6nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 6(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  11nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  12nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 13(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  17nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 9(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  25nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 14(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  41nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 5B, mitochondrial(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  54nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  54nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  63nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  89nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  250nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 14(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  2.27E+3nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  2.44E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  3.86E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  3.92E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetCarbonic anhydrase 13(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  4.17E+3nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetCarbonic anhydrase 4(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 4(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetCarbonic anhydrase 7(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  7.55E+3nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  7.95E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetCarbonic anhydrase 6(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  9.20E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  7.80E+5nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed