Compile Data Set for Download or QSAR

Found 583 hits of Enzyme Inhibition Constant Data   

TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225469(GTC000178A)
Show SMILES CC(C)ONS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)c1
Show InChI InChI=1S/C20H21N7O3S/c1-13(2)30-27-31(28,29)15-6-3-5-14(11-15)23-20-21-10-9-19(25-20)24-17-7-4-8-18-16(17)12-22-26-18/h3-13,27H,1-2H3,(H,22,26)(H2,21,23,24,25)
Affinity DataIC50: 685nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225493(GTC000202A)
Show SMILES O=C1CCCN1CCCNS(=O)(=O)Cc1ccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc1
Show InChI InChI=1S/C25H28N8O3S/c34-24-6-2-14-33(24)15-3-12-28-37(35,36)17-18-7-9-19(10-8-18)29-25-26-13-11-23(31-25)30-21-4-1-5-22-20(21)16-27-32-22/h1,4-5,7-11,13,16,28H,2-3,6,12,14-15,17H2,(H,27,32)(H2,26,29,30,31)
Affinity DataIC50: 706nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225464(GTC000173A)
Show SMILES C(Oc1cccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)c1)c1ccccc1
Show InChI InChI=1S/C24H20N6O/c1-2-6-17(7-3-1)16-31-19-9-4-8-18(14-19)27-24-25-13-12-23(29-24)28-21-10-5-11-22-20(21)15-26-30-22/h1-15H,16H2,(H,26,30)(H2,25,27,28,29)
Affinity DataIC50: 710nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225480(GTC000189A)
Show SMILES Cc1cc(NS(=O)(=O)c2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc2)no1
Show InChI InChI=1S/C21H18N8O3S/c1-13-11-20(28-32-13)29-33(30,31)15-7-5-14(6-8-15)24-21-22-10-9-19(26-21)25-17-3-2-4-18-16(17)12-23-27-18/h2-12H,1H3,(H,23,27)(H,28,29)(H2,22,24,25,26)
Affinity DataIC50: 741nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225494(GTC000203A)
Show SMILES OCCCNS(=O)(=O)Cc1ccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc1
Show InChI InChI=1S/C21H23N7O3S/c29-12-2-10-24-32(30,31)14-15-5-7-16(8-6-15)25-21-22-11-9-20(27-21)26-18-3-1-4-19-17(18)13-23-28-19/h1,3-9,11,13,24,29H,2,10,12,14H2,(H,23,28)(H2,22,25,26,27)
Affinity DataIC50: 746nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225435(GTC000143A)
Show SMILES O=C1OCc2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc12
Show InChI InChI=1S/C19H14N6O2/c26-18-13-8-12(5-4-11(13)10-27-18)22-19-20-7-6-17(24-19)23-15-2-1-3-16-14(15)9-21-25-16/h1-9H,10H2,(H,21,25)(H2,20,22,23,24)
Affinity DataIC50: 767nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225466(GTC000175A)
Show SMILES CN(C(C)=O)c1ccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc1
Show InChI InChI=1S/C20H19N7O/c1-13(28)27(2)15-8-6-14(7-9-15)23-20-21-11-10-19(25-20)24-17-4-3-5-18-16(17)12-22-26-18/h3-12H,1-2H3,(H,22,26)(H2,21,23,24,25)
Affinity DataIC50: 793nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225507(GTC000216A)
Show SMILES O=C(Cc1ccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc1)Nc1ccncc1
Show InChI InChI=1S/C24H20N8O/c33-23(28-18-8-11-25-12-9-18)14-16-4-6-17(7-5-16)29-24-26-13-10-22(31-24)30-20-2-1-3-21-19(20)15-27-32-21/h1-13,15H,14H2,(H,27,32)(H,25,28,33)(H2,26,29,30,31)
Affinity DataIC50: 828nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225499(GTC000208A)
Show SMILES COc1ccc(NC(=O)Cc2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc2)cc1
Show InChI InChI=1S/C26H23N7O2/c1-35-20-11-9-18(10-12-20)29-25(34)15-17-5-7-19(8-6-17)30-26-27-14-13-24(32-26)31-22-3-2-4-23-21(22)16-28-33-23/h2-14,16H,15H2,1H3,(H,28,33)(H,29,34)(H2,27,30,31,32)
Affinity DataIC50: 849nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225491(GTC000200A)
Show SMILES Cc1noc(NS(=O)(=O)Cc2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc2)c1C
Show InChI InChI=1S/C23H22N8O3S/c1-14-15(2)30-34-22(14)31-35(32,33)13-16-6-8-17(9-7-16)26-23-24-11-10-21(28-23)27-19-4-3-5-20-18(19)12-25-29-20/h3-12,31H,13H2,1-2H3,(H,25,29)(H2,24,26,27,28)
Affinity DataIC50: 887nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225511(GTC000220A)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc1
Show InChI InChI=1S/C24H21N7O2S/c1-16-5-11-19(12-6-16)34(32,33)31-18-9-7-17(8-10-18)27-24-25-14-13-23(29-24)28-21-3-2-4-22-20(21)15-26-30-22/h2-15,31H,1H3,(H,26,30)(H2,25,27,28,29)
Affinity DataIC50: 916nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225427(GTC000135A)
Show SMILES COc1ccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc1
Show InChI InChI=1S/C18H16N6O/c1-25-13-7-5-12(6-8-13)21-18-19-10-9-17(23-18)22-15-3-2-4-16-14(15)11-20-24-16/h2-11H,1H3,(H,20,24)(H2,19,21,22,23)
Affinity DataIC50: 923nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225496(GTC000205A)
Show SMILES Cc1noc(NC(=O)Cc2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc2)c1C
Show InChI InChI=1S/C24H22N8O2/c1-14-15(2)32-34-23(14)30-22(33)12-16-6-8-17(9-7-16)27-24-25-11-10-21(29-24)28-19-4-3-5-20-18(19)13-26-31-20/h3-11,13H,12H2,1-2H3,(H,26,31)(H,30,33)(H2,25,27,28,29)
Affinity DataIC50: 925nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225480(GTC000189A)
Show SMILES Cc1cc(NS(=O)(=O)c2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc2)no1
Show InChI InChI=1S/C21H18N8O3S/c1-13-11-20(28-32-13)29-33(30,31)15-7-5-14(6-8-15)24-21-22-10-9-19(26-21)25-17-3-2-4-18-16(17)12-23-27-18/h2-12H,1H3,(H,23,27)(H,28,29)(H2,22,24,25,26)
Affinity DataIC50: 942nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225478(GTC000187A)
Show SMILES Cc1noc(NS(=O)(=O)c2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc2)c1C
Show InChI InChI=1S/C22H20N8O3S/c1-13-14(2)29-33-21(13)30-34(31,32)16-8-6-15(7-9-16)25-22-23-11-10-20(27-22)26-18-4-3-5-19-17(18)12-24-28-19/h3-12,30H,1-2H3,(H,24,28)(H2,23,25,26,27)
Affinity DataIC50: 971nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225503(GTC000212A)
Show SMILES FC(F)(F)c1cccc(NC(=O)Cc2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc2)c1
Show InChI InChI=1S/C26H20F3N7O/c27-26(28,29)17-3-1-4-19(14-17)32-24(37)13-16-7-9-18(10-8-16)33-25-30-12-11-23(35-25)34-21-5-2-6-22-20(21)15-31-36-22/h1-12,14-15H,13H2,(H,31,36)(H,32,37)(H2,30,33,34,35)
Affinity DataIC50: 1.04E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225492(GTC000201A)
Show SMILES Cc1nc(NS(=O)(=O)Cc2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc2)sc1C
Show InChI InChI=1S/C23H22N8O2S2/c1-14-15(2)34-23(26-14)31-35(32,33)13-16-6-8-17(9-7-16)27-22-24-11-10-21(29-22)28-19-4-3-5-20-18(19)12-25-30-20/h3-12H,13H2,1-2H3,(H,25,30)(H,26,31)(H2,24,27,28,29)
Affinity DataIC50: 1.10E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225481(GTC000190A)
Show SMILES OS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)c1
Show InChI InChI=1S/C17H14N6O3S/c24-27(25,26)12-4-1-3-11(9-12)20-17-18-8-7-16(22-17)21-14-5-2-6-15-13(14)10-19-23-15/h1-10H,(H,19,23)(H,24,25,26)(H2,18,20,21,22)
Affinity DataIC50: 1.10E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225485(GTC000194A)
Show SMILES CC(C)(C)OC(=O)COc1ccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc1
Show InChI InChI=1S/C23H24N6O3/c1-23(2,3)32-21(30)14-31-16-9-7-15(8-10-16)26-22-24-12-11-20(28-22)27-18-5-4-6-19-17(18)13-25-29-19/h4-13H,14H2,1-3H3,(H,25,29)(H2,24,26,27,28)
Affinity DataIC50: 1.18E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225509(GTC000218A)
Show SMILES CNC(=O)Cc1ccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc1
Show InChI InChI=1S/C20H19N7O/c1-21-19(28)11-13-5-7-14(8-6-13)24-20-22-10-9-18(26-20)25-16-3-2-4-17-15(16)12-23-27-17/h2-10,12H,11H2,1H3,(H,21,28)(H,23,27)(H2,22,24,25,26)
Affinity DataIC50: 1.26E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225479(GTC000188A)
Show SMILES O=S(=O)(N1CCCC1)c1ccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc1
Show InChI InChI=1S/C21H21N7O2S/c29-31(30,28-12-1-2-13-28)16-8-6-15(7-9-16)24-21-22-11-10-20(26-21)25-18-4-3-5-19-17(18)14-23-27-19/h3-11,14H,1-2,12-13H2,(H,23,27)(H2,22,24,25,26)
Affinity DataIC50: 1.34E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225478(GTC000187A)
Show SMILES Cc1noc(NS(=O)(=O)c2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc2)c1C
Show InChI InChI=1S/C22H20N8O3S/c1-13-14(2)29-33-21(13)30-34(31,32)16-8-6-15(7-9-16)25-22-23-11-10-20(27-22)26-18-4-3-5-19-17(18)12-24-28-19/h3-12,30H,1-2H3,(H,24,28)(H2,23,25,26,27)
Affinity DataIC50: 1.38E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225504(GTC000213A)
Show SMILES Clc1cccc(NC(=O)Cc2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc2)c1
Show InChI InChI=1S/C25H20ClN7O/c26-17-3-1-4-19(14-17)29-24(34)13-16-7-9-18(10-8-16)30-25-27-12-11-23(32-25)31-21-5-2-6-22-20(21)15-28-33-22/h1-12,14-15H,13H2,(H,28,33)(H,29,34)(H2,27,30,31,32)
Affinity DataIC50: 1.39E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225505(GTC000214A)
Show SMILES Clc1ccc(NC(=O)Cc2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc2)cc1
Show InChI InChI=1S/C25H20ClN7O/c26-17-6-10-18(11-7-17)29-24(34)14-16-4-8-19(9-5-16)30-25-27-13-12-23(32-25)31-21-2-1-3-22-20(21)15-28-33-22/h1-13,15H,14H2,(H,28,33)(H,29,34)(H2,27,30,31,32)
Affinity DataIC50: 1.40E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225485(GTC000194A)
Show SMILES CC(C)(C)OC(=O)COc1ccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc1
Show InChI InChI=1S/C23H24N6O3/c1-23(2,3)32-21(30)14-31-16-9-7-15(8-10-16)26-22-24-12-11-20(28-22)27-18-5-4-6-19-17(18)13-25-29-19/h4-13H,14H2,1-3H3,(H,25,29)(H2,24,26,27,28)
Affinity DataIC50: 1.64E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225479(GTC000188A)
Show SMILES O=S(=O)(N1CCCC1)c1ccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc1
Show InChI InChI=1S/C21H21N7O2S/c29-31(30,28-12-1-2-13-28)16-8-6-15(7-9-16)24-21-22-11-10-20(26-21)25-18-4-3-5-19-17(18)14-23-27-19/h3-11,14H,1-2,12-13H2,(H,23,27)(H2,22,24,25,26)
Affinity DataIC50: 1.80E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225491(GTC000200A)
Show SMILES Cc1noc(NS(=O)(=O)Cc2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc2)c1C
Show InChI InChI=1S/C23H22N8O3S/c1-14-15(2)30-34-22(14)31-35(32,33)13-16-6-8-17(9-7-16)26-23-24-11-10-21(28-23)27-19-4-3-5-20-18(19)12-25-29-20/h3-12,31H,13H2,1-2H3,(H,25,29)(H2,24,26,27,28)
Affinity DataIC50: 1.82E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225485(GTC000194A)
Show SMILES CC(C)(C)OC(=O)COc1ccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc1
Show InChI InChI=1S/C23H24N6O3/c1-23(2,3)32-21(30)14-31-16-9-7-15(8-10-16)26-22-24-12-11-20(28-22)27-18-5-4-6-19-17(18)13-25-29-19/h4-13H,14H2,1-3H3,(H,25,29)(H2,24,26,27,28)
Affinity DataIC50: 1.96E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
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TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225495(GTC000204A)
Show SMILES O=C(COc1ccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc1)NCCCN1CCCC1=O
Show InChI InChI=1S/C26H28N8O3/c35-24(27-12-3-15-34-14-2-6-25(34)36)17-37-19-9-7-18(8-10-19)30-26-28-13-11-23(32-26)31-21-4-1-5-22-20(21)16-29-33-22/h1,4-5,7-11,13,16H,2-3,6,12,14-15,17H2,(H,27,35)(H,29,33)(H2,28,30,31,32)
Affinity DataIC50: 2.07E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225502(GTC000211A)
Show SMILES FC(F)(F)c1ccc(NC(=O)Cc2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc2)cc1
Show InChI InChI=1S/C26H20F3N7O/c27-26(28,29)17-6-10-18(11-7-17)32-24(37)14-16-4-8-19(9-5-16)33-25-30-13-12-23(35-25)34-21-2-1-3-22-20(21)15-31-36-22/h1-13,15H,14H2,(H,31,36)(H,32,37)(H2,30,33,34,35)
Affinity DataIC50: 2.93E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225470(GTC000179A)
Show SMILES O=S(=O)(N1CCCCC1)c1cccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)c1
Show InChI InChI=1S/C22H23N7O2S/c30-32(31,29-12-2-1-3-13-29)17-7-4-6-16(14-17)25-22-23-11-10-21(27-22)26-19-8-5-9-20-18(19)15-24-28-20/h4-11,14-15H,1-3,12-13H2,(H,24,28)(H2,23,25,26,27)
Affinity DataIC50: 4.16E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225476(GTC000185A)
Show SMILES CN1CCN(CC1)C(=O)c1ccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc1
Show InChI InChI=1S/C23H24N8O/c1-30-11-13-31(14-12-30)22(32)16-5-7-17(8-6-16)26-23-24-10-9-21(28-23)27-19-3-2-4-20-18(19)15-25-29-20/h2-10,15H,11-14H2,1H3,(H,25,29)(H2,24,26,27,28)
Affinity DataIC50: 4.19E+3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225502(GTC000211A)
Show SMILES FC(F)(F)c1ccc(NC(=O)Cc2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc2)cc1
Show InChI InChI=1S/C26H20F3N7O/c27-26(28,29)17-6-10-18(11-7-17)32-24(37)14-16-4-8-19(9-5-16)33-25-30-13-12-23(35-25)34-21-2-1-3-22-20(21)15-31-36-22/h1-13,15H,14H2,(H,31,36)(H,32,37)(H2,30,33,34,35)
Affinity DataIC50: 1.58E+4nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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