Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50003694
TargetBeta-lactamase(Proteus mirabilis)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50021959(CHEMBL777 | MM 14151 | US9120808, Clavulanic acid ...)
Affinity DataIC50:  95.4nMAssay Description:Inhibition of Proteus mirabilis C889 beta-lactamase assessed as inhibition of nitrocefin hydrolysis preincubated for 5 mins by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-lactamase TEM(Escherichia coli)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50021959(CHEMBL777 | MM 14151 | US9120808, Clavulanic acid ...)
Affinity DataIC50:  145nMAssay Description:Inhibition of Escherichia coli JT4 beta-lactamase TEM1 assessed as inhibition of nitrocefin hydrolysis preincubated for 5 mins by microtiter plate as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-lactamase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50021959(CHEMBL777 | MM 14151 | US9120808, Clavulanic acid ...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Staphylococcus aureus Russell beta-lactamase assessed as inhibition of nitrocefin hydrolysis pre-incubated for 5 mins by microtiter pla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetBeta-lactamase TEM(Escherichia coli)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50469657(CHEMBL33995 | SB-202742)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of Escherichia coli JT4 beta-lactamase TEM1 assessed as inhibition of nitrocefin hydrolysis preincubated for 5 mins by microtiter plate as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-lactamase(Enterobacter cloacae)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50469657(CHEMBL33995 | SB-202742)
Affinity DataIC50:  4.58E+4nMAssay Description:Inhibition of Enterobacter cloacae P99 beta-lactamase assessed as inhibition of nitrocefin hydrolysis pre-incubated for 5 mins by microtiter plate as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-lactamase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50469657(CHEMBL33995 | SB-202742)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa A beta-lactamase assessed as inhibition of nitrocefin hydrolysis preincubated for 5 mins by microtiter plate ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-lactamase(Proteus mirabilis)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50469657(CHEMBL33995 | SB-202742)
Affinity DataIC50:  2.99E+5nMAssay Description:Inhibition of Proteus mirabilis C889 beta-lactamase assessed as inhibition of nitrocefin hydrolysis preincubated for 5 mins by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-lactamase(Enterobacter cloacae)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50021959(CHEMBL777 | MM 14151 | US9120808, Clavulanic acid ...)
Affinity DataIC50:  7.78E+5nMAssay Description:Inhibition of Enterobacter cloacae P99 beta-lactamase assessed as inhibition of nitrocefin hydrolysis pre-incubated for 5 mins by microtiter plate as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-lactamase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50021959(CHEMBL777 | MM 14151 | US9120808, Clavulanic acid ...)
Affinity DataIC50:  3.71E+6nMAssay Description:Inhibition of Pseudomonas aeruginosa A beta-lactamase assessed as inhibition of nitrocefin hydrolysis preincubated for 5 mins by microtiter plate ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed