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Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50036320
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453639(CHEMBL2112889)
Affinity DataIC50:  0.360nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50006784(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041282((3S,8R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453639(CHEMBL2112889)
Affinity DataIC50:  0.690nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453638(CHEMBL2112877)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50035738((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453638(CHEMBL2112877)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041282((3S,8R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50012154((3S,8R)-3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041282((3S,8R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453639(CHEMBL2112889)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453640(CHEMBL2112860)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50451132(CHEMBL2079586 | WIN-35428)
Affinity DataIC50:  16nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50012154((3S,8R)-3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50:  19nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50366564(CHEMBL1790051 | CHEMBL83729 | WIN-35065-2)
Affinity DataIC50:  23nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50118185((3S,8R)-3-(4-Ethyl-phenyl)-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041281((3S,8R)-3-Phenyl-8-aza-bicyclo[3.2.1]octane-2-carb...)
Affinity DataIC50:  31nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)
Affinity DataIC50:  36nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50035738((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  37nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50035738((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  45nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453640(CHEMBL2112860)
Affinity DataIC50:  50nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50118185((3S,8R)-3-(4-Ethyl-phenyl)-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50:  55nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50006784(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50:  67nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50012154((3S,8R)-3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50:  69nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041281((3S,8R)-3-Phenyl-8-aza-bicyclo[3.2.1]octane-2-carb...)
Affinity DataIC50:  85nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  89nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453640(CHEMBL2112860)
Affinity DataIC50:  122nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041285((3S,8R)-3-Benzoyloxy-8-aza-bicyclo[3.2.1]octane-2-...)
Affinity DataIC50:  127nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453638(CHEMBL2112877)
Affinity DataIC50:  132nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041285((3S,8R)-3-Benzoyloxy-8-aza-bicyclo[3.2.1]octane-2-...)
Affinity DataIC50:  139nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041281((3S,8R)-3-Phenyl-8-aza-bicyclo[3.2.1]octane-2-carb...)
Affinity DataIC50:  156nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041285((3S,8R)-3-Benzoyloxy-8-aza-bicyclo[3.2.1]octane-2-...)
Affinity DataIC50:  206nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50006784(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50:  285nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50451132(CHEMBL2079586 | WIN-35428)
Affinity DataIC50:  759nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50451132(CHEMBL2079586 | WIN-35428)
Affinity DataIC50:  834nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50366564(CHEMBL1790051 | CHEMBL83729 | WIN-35065-2)
Affinity DataIC50:  920nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50366564(CHEMBL1790051 | CHEMBL83729 | WIN-35065-2)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50118185((3S,8R)-3-(4-Ethyl-phenyl)-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50:  3.91E+3nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed